Collecting ovarian tissue samples from girls undergoing surgery

Pediatric Ovarian Tissue Banking - Operative Specimens From Females 0-18 Years of Age

Ann & Robert H Lurie Children's Hospital of Chicago · NCT04118712

This study is collecting leftover ovarian tissue from girls and women aged 0-18 who are having surgery to see how different ovarian conditions impact fertility.

Quick facts

Study typeObservational
Enrollment100 (estimated)
AgesN/A to 18 Years
SexFemale
SponsorAnn & Robert H Lurie Children's Hospital of Chicago (other)
Locations1 site (Chicago, Illinois)
Trial IDNCT04118712 on ClinicalTrials.gov

What this trial studies

This observational study aims to enroll girls and women aged 0-18 who are undergoing surgery involving the ovary, such as oophorectomy or ovarian cystectomy. The investigators will collect discarded ovarian tissue samples during these procedures to create an ovarian tissue library. The goal is to analyze how various ovarian conditions affect the number and quality of ovarian follicles and the overall reproductive potential of the ovary. No additional procedures will be performed solely for the study, ensuring that only tissue that would otherwise be discarded is collected.

Who should consider this trial

Good fit: Ideal candidates are pre and post pubertal females aged 0-18 undergoing scheduled or emergent surgeries involving the ovary.

Not a fit: Patients who are pregnant will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of ovarian health and improve future reproductive outcomes for young females.

How similar studies have performed: While similar studies have explored ovarian tissue banking, this specific approach focusing on pediatric patients is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Pre and Post Pubertal females
* Ages 0-18 years old
* Undergoing scheduled or emergent operative procedures involving the ovary

  1. oophorectomy (torsion, benign mass/cyst, malignant mass/cyst)
  2. ovarian cystectomy

Exclusion Criteria:

* Pregnant females

Where this trial is running

Chicago, Illinois

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Benign Cysts Ovarian, Cystectomy, Torsion, Malignant Cysts Ovarian

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.