Using brain stimulation to help reduce opioid relapse
Official title: tDCS to Decrease Opioid Relapse
Funded at Butler Hospital (Providence, Ri) · NIH-11003758 · Data updated 2026-11-12
This study is looking at whether a gentle brain stimulation technique can help people starting treatment with buprenorphine for opioid use disorder by reducing cravings and improving focus, making it easier for them to stay on track during their recovery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Butler Hospital (Providence, Ri) NIH-funded |
| Lab location | 1 site (Providence, United States) |
| Project start | September 30, 2018 |
| Project end | December 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $496,284 |
| NIH project number | 5UH3DA047793-04 |
| Project ID | NIH-11003758 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals beginning treatment with buprenorphine for opioid use disorder.
✕Less likely to help
Patients who are not starting buprenorphine treatment or those with other substance use disorders may not benefit from this research.
What this research studies
This research investigates the use of transcranial direct current stimulation (tDCS) as an additional treatment for individuals starting buprenorphine for opioid use disorder. The study focuses on stimulating a specific brain region involved in self-regulation to potentially decrease cravings and improve cognitive control. Participants will undergo brain imaging before and after the stimulation sessions to assess changes in brain activity and craving levels. The goal is to determine if this approach can help reduce the likelihood of relapse in patients during their initial treatment phase.
Why it matters
Potential benefit: If successful, this research could provide a new method to help individuals maintain abstinence from opioids and reduce relapse rates.
How similar studies have gone: Previous research has shown promise in using brain stimulation techniques for addiction treatment, suggesting potential for success in this approach.
Where this research is happening
-
Butler Hospital (Providence, Ri)
Providence, United States Active
Researchers
- Principal investigator: Abrantes, Ana M — Butler Hospital (Providence, Ri)
- Study coordinator: Abrantes, Ana M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.