Understanding Speech in Autism

Neural mechanisms of speech motor control in Autism Spectrum Disorders

NIH-funded research University of California, San Francisco · NIH-11098471

This project looks at how the brain controls speech in children and teenagers with Autism Spectrum Disorder to help us find better ways to support their communication.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-11098471 on NIH RePORTER

What this research studies

Many children and teenagers with Autism Spectrum Disorder (ASD) find it hard to speak, and we don't fully understand why. This project uses special brain imaging techniques and behavioral tasks to learn more about how their brains process sounds and control speech. By looking at brain chemicals and how different brain areas connect, we hope to pinpoint the specific challenges that make speaking difficult for them. This deeper understanding could pave the way for new and more effective therapies.

Who could benefit from this research

Good fit: Ideal candidates for future related studies would be children and adolescents, both with and without Autism Spectrum Disorder, who are experiencing speech difficulties.

Not a fit: Patients who do not have Autism Spectrum Disorder or speech difficulties related to it may not directly benefit from this specific line of research.

Why it matters

Potential benefit: If successful, this work could lead to new, targeted treatments that address the root causes of speech difficulties in individuals with Autism Spectrum Disorder.

How similar studies have performed: Preliminary work has shown that changing how individuals with ASD hear their own speech can affect their speaking, providing a foundation for this deeper exploration of brain mechanisms.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.