NIH-funded research R21 grant

Understanding how context affects speech processing in autism.

Official title: The Role of Context in the Neural Processing of Speech in Autism Spectrum Disorder

Funded at Northwestern University · NIH-10973742 · Data updated 2026-11-12

This study is looking at how people with autism understand speech, especially when there’s a lot of background noise, to help find better ways for them to communicate and connect with others.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionNorthwestern University
NIH-funded
Lab location1 site (Chicago, UNITED STATES)
Project startJuly 1, 2024
Project endJune 30, 2027
Funding year2024
Award (this year)$200,000
NIH project number1R21DC022031-01
Project IDNIH-10973742 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with autism spectrum disorder who experience difficulties in speech processing and social communication.

Less likely to help

Patients without a diagnosis of autism spectrum disorder or those who do not experience speech processing challenges may not benefit from this research.

What this research studies

This research investigates how individuals with autism spectrum disorder (ASD) process speech differently, particularly in understanding social and emotional cues and in noisy environments. The study aims to uncover the brain mechanisms behind these challenges by examining the balance between top-down and local processing of speech signals. Using advanced techniques like electroencephalography (EEG), researchers will analyze how autistic individuals use contextual information to filter out irrelevant sounds and focus on important speech elements. The findings could lead to better strategies for improving communication in individuals with ASD.

Why it matters

Potential benefit: If successful, this research could enhance communication strategies for individuals with autism, improving their social interactions and overall quality of life.

How similar studies have gone: Previous studies have shown promising results in understanding auditory processing in typical development, suggesting that this approach could yield valuable insights for autism as well.

Where this research is happening

  • Northwestern University
    Chicago, United States
    Active

Researchers

  • Principal investigator: Lau, Chung Yin Joseph — Northwestern University
  • Study coordinator: Lau, Chung Yin Joseph

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.