Understanding how gut bacteria stability affects inflammatory bowel disease

Who could benefit from this research

What this research studies

This research investigates the role of gut microbiota stability in patients with Inflammatory Bowel Disease (IBD), which includes conditions like Ulcerative Colitis and Crohn's Disease. Over a period of five years, researchers will collect and analyze fecal samples from individuals with IBD and healthy controls to identify differences in gut bacteria. They will also study patients who have undergone fecal microbiota transplantation to see how the gut microbiota changes over time and its impact on disease remission. The goal is to understand how certain bacteria contribute to inflammation and disease progression.

Why it matters

Where this research is happening

• Icahn School of Medicine at Mount Sinai
  New York, United States Active

Researchers

• Principal investigator: Faith, Jeremiah James — Icahn School of Medicine at Mount Sinai
• Study coordinator: Faith, Jeremiah James

Related research

Other NIH-funded projects on the same topics.

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• Gut bacteria stability in ulcerative colitis and Crohn’s disease

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  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11296873

• Gut microbes, fiber in your diet, and inflammatory bowel disease

  This grant explores how dietary fiber and gut bacteria influence inflammatory bowel disease and related inflammation in people and models.

  NIH research Georgia State University · Atlanta, United States · NIH-11288589

• How processed diets and gut bacteria affect inflammatory bowel disease

  This study is looking at how eating a lot of processed foods might affect gut bacteria and the immune system, which could increase the risk of inflammatory bowel disease (IBD), and it aims to find ways to improve diets to help prevent or reduce IBD.

  NIH research Pennsylvania State University, the · University Park, United States · NIH-11083565

• Gut microbiome and Parkinson's disease: how gut bugs relate to symptoms and progression

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  NIH research University of Chicago · Chicago, United States · NIH-11583671

• Gut-Brain Axis in Parkinson’s Disease: biomarkers and procedures to track progression

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.