Understanding how gut bacteria stability affects inflammatory bowel disease
The Influence Of Gut Microbiota Stability In Inflammatory Bowel Disease
This study is looking at how the balance of gut bacteria affects people with Inflammatory Bowel Disease (IBD), like Ulcerative Colitis and Crohn's Disease, by comparing their gut samples to those of healthy individuals and tracking changes in bacteria after treatments to help improve their health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11083621 on NIH RePORTER |
What this research studies
This research investigates the role of gut microbiota stability in patients with Inflammatory Bowel Disease (IBD), which includes conditions like Ulcerative Colitis and Crohn's Disease. Over a period of five years, researchers will collect and analyze fecal samples from individuals with IBD and healthy controls to identify differences in gut bacteria. They will also study patients who have undergone fecal microbiota transplantation to see how the gut microbiota changes over time and its impact on disease remission. The goal is to understand how certain bacteria contribute to inflammation and disease progression.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Inflammatory Bowel Disease, including Ulcerative Colitis and Crohn's Disease.
Not a fit: Patients without a diagnosis of Inflammatory Bowel Disease or those with other unrelated gastrointestinal conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients with inflammatory bowel disease by identifying key bacterial strains that influence disease stability and remission.
How similar studies have performed: Previous research has shown promising results in understanding the gut microbiome's role in inflammatory bowel diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Faith, Jeremiah James — Icahn School of Medicine at Mount Sinai
- Study coordinator: Faith, Jeremiah James
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.