Gut microbes, fiber in your diet, and inflammatory bowel disease
Official title: Gut microbiota, dietary fiber, and inflammatory bowel disease
Funded at Georgia State University · NIH-11288589 · Data updated 2026-11-12
This grant explores how dietary fiber and gut bacteria influence inflammatory bowel disease and related inflammation in people and models.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgia State University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | July 15, 2026 |
| Project end | June 30, 2030 |
| Funding year | 2026 |
| Award (this year) | $786,149 |
| NIH project number | 1R01DK146134-01 |
| Project ID | NIH-11288589 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals with inflammatory bowel disease or chronic inflammatory conditions who are interested in how fiber in the diet might influence their disease, potentially as future trial participants or for matched dietary guidance.
✕Less likely to help
Patients without inflammatory bowel disease or those not following a fiber-rich dietary approach may see limited direct benefit.
What this research studies
The project examines how different types of dietary fiber affect intestinal inflammation and the gut microbiome, using mouse models to understand mechanisms that could apply to people with inflammatory bowel disease. It will look at how fiber changes gut bacteria and inflammatory signals, aiming to identify fiber strategies that may help manage IBD and related conditions. The work seeks to translate findings toward dietary guidance or future clinical studies that could benefit patients with chronic inflammatory diseases.
Why it matters
Potential benefit: If successful, the research could inform personalized dietary recommendations to help reduce intestinal inflammation in patients with IBD and related chronic diseases.
How similar studies have gone: Previous animal studies suggest fiber can modulate inflammation, but human relevance remains to be clarified, making this work both promising and exploratory for patients.
Where this research is happening
-
Georgia State University
Atlanta, United States Active
Researchers
- Principal investigator: Gewirtz, Andrew T — Georgia State University
- Study coordinator: Gewirtz, Andrew T
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.