Understanding how aging with HIV affects brain and movement functions
Official title: Neurofunctional Mechanisms of Changes in Cognition and Motor Function in Aging with HIV and Parkinson's Disease
Funded at Sri International · NIH-11082280 · Data updated 2026-11-12
This study is looking at how aging with HIV affects the brain and movement in older adults, especially in ways that might be similar to Parkinson's disease, to help improve understanding and treatment for those experiencing these changes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sri International NIH-funded |
| Lab location | 1 site (Menlo Park, United States) |
| Project start | May 15, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $784,552 |
| NIH project number | 5R01AG081144-03 |
| Project ID | NIH-11082280 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 50 and older who are living with HIV.
✕Less likely to help
Patients who are younger than 50 or do not have HIV may not benefit from this research.
What this research studies
This research investigates the neurological and cognitive changes that occur in older adults living with HIV, particularly focusing on how these changes relate to motor functions similar to those seen in Parkinson's disease. By utilizing neuroimaging techniques, the study aims to identify specific brain patterns that correlate with cognitive decline and motor symptoms. Participants will undergo assessments to evaluate their cognitive abilities and motor skills, helping researchers understand the complexities of aging with HIV. The findings could lead to better diagnostic tools and treatment strategies for this population.
Why it matters
Potential benefit: If successful, this research could improve the understanding and management of cognitive and motor impairments in older adults living with HIV.
How similar studies have gone: Previous research has shown promising results in understanding cognitive decline in aging populations, but this specific focus on HIV and Parkinson's disease is relatively novel.
Where this research is happening
-
Sri International
Menlo Park, United States Active
Researchers
- Principal investigator: Schulte, Tilman — Sri International
- Study coordinator: Schulte, Tilman
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.