Understanding how aging with HIV affects brain and movement functions

Neurofunctional Mechanisms of Changes in Cognition and Motor Function in Aging with HIV and Parkinson's Disease

NIH-funded research Sri International · NIH-11082280

This study is looking at how aging with HIV affects the brain and movement in older adults, especially in ways that might be similar to Parkinson's disease, to help improve understanding and treatment for those experiencing these changes.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSri International NIH-funded
Lab location1 site (Menlo Park, United States)
Project IDNIH-11082280 on NIH RePORTER

What this research studies

This research investigates the neurological and cognitive changes that occur in older adults living with HIV, particularly focusing on how these changes relate to motor functions similar to those seen in Parkinson's disease. By utilizing neuroimaging techniques, the study aims to identify specific brain patterns that correlate with cognitive decline and motor symptoms. Participants will undergo assessments to evaluate their cognitive abilities and motor skills, helping researchers understand the complexities of aging with HIV. The findings could lead to better diagnostic tools and treatment strategies for this population.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 50 and older who are living with HIV.

Not a fit: Patients who are younger than 50 or do not have HIV may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could improve the understanding and management of cognitive and motor impairments in older adults living with HIV.

How similar studies have performed: Previous research has shown promising results in understanding cognitive decline in aging populations, but this specific focus on HIV and Parkinson's disease is relatively novel.

Where this research is happening

Menlo Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.