Understanding how cognition and personality change in aging and Alzheimer's disease.
Within-person dynamics of cognition and personality in healthy aging and Alzheimer's disease.
['FUNDING_CAREER'] · WASHINGTON UNIVERSITY · NIH-11023137
This study is looking at how thinking skills and personality change as people get older, especially for those with Alzheimer's, to help find better ways to track these changes and improve care for patients.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-11023137 on ClinicalTrials.gov |
What this research studies
This research investigates the fluctuations in cognitive function and personality traits in individuals as they age, particularly those with Alzheimer's disease. By using advanced statistical models, the study aims to capture daily variations in cognitive performance, which may reflect underlying biological and psychological processes. Participants will undergo assessments over a three-week period to identify patterns that could predict cognitive decline. The goal is to improve the measurement of cognitive function in clinical trials, potentially leading to better outcomes for patients.
Who could benefit from this research
Good fit: Ideal candidates include adults aged 21 and older, particularly those with mild cognitive impairment or at risk for Alzheimer's disease.
Not a fit: Patients with severe cognitive impairment or those not at risk for Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate assessments of cognitive decline, improving treatment strategies for Alzheimer's disease.
How similar studies have performed: Other research has shown promise in using intensive longitudinal methods to understand cognitive variability, suggesting this approach could be effective.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ASCHENBRENNER, ANDREW — WASHINGTON UNIVERSITY
- Study coordinator: ASCHENBRENNER, ANDREW
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome