Investigating risk factors for Alzheimer's disease and related dementias in Kenyan adults.
Official title: Measurement and Analysis of Aging, Cognition and Alzheimer's Disease and Related Dementia (ADRD) Risk Factors at Midlife in the Kenya Life Panel Survey (KLPS)
Funded at University of California Berkeley · NIH-11082349 · Data updated 2026-11-12
This study is looking at what might increase the chances of developing Alzheimer's and related dementias in Kenyan adults aged 35 to 43, by exploring how their health, education, and social attitudes have changed since childhood.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Berkeley NIH-funded |
| Lab location | 1 site (Berkeley, United States) |
| Project start | May 15, 2022 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $663,557 |
| NIH project number | 5R01AG077001-04 |
| Project ID | NIH-11082349 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Kenyan adults aged 35 to 43 who have been part of the Kenya Life Panel Survey.
✕Less likely to help
Patients outside the age range of 35 to 43 or those not part of the Kenya Life Panel Survey may not benefit from this research.
What this research studies
This research focuses on understanding the risk factors associated with Alzheimer's disease and related dementias (AD/ADRD) among Kenyan adults. By utilizing the Kenya Life Panel Survey (KLPS), which has tracked a cohort of individuals since childhood, the study aims to gather detailed cognitive and health data from participants aged 35 to 43. The research will analyze how various factors, including health, education, and social attitudes, influence the development of AD/ADRD over time. This comprehensive approach allows for a unique examination of cognitive changes and risk factors throughout different life stages.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for Alzheimer's disease in Sub-Saharan Africa.
How similar studies have gone: While research on Alzheimer's disease in Sub-Saharan Africa is limited, similar longitudinal studies in other regions have successfully identified risk factors for dementia.
Where this research is happening
-
University of California Berkeley
Berkeley, United States Active
Researchers
- Principal investigator: Miguel, Edward Andrew — University of California Berkeley
- Study coordinator: Miguel, Edward Andrew
Related research
Other NIH-funded projects on the same topics.
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Midlife memory and dementia risk in Kenyan adults
This work looks at midlife thinking and memory and how childhood health and life experiences might affect future dementia risk for Kenyan adults.
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A study of adults with Down syndrome to see if everyday ups and downs in thinking tests can predict Alzheimer’s-related changes and dementia using blood and brain biomarkers.
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This project looks at whether ups-and-downs in thinking tests can signal early Alzheimer's in adults with Down syndrome.
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Beaver Dam Offspring Study: How midlife senses and aging markers relate to early Alzheimer’s and dementia
This study follows adults who previously participated in a long-term cohort to see if midlife changes in hearing, vision, smell, and aging biomarkers can predict later risk of Alzheimer’s disease and related dementias.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.