Transdiagnostic therapy to improve mental health and TB treatment outcomes in India
Official title: Effectiveness and implementation of a transdiagnostic therapy for addressing mental and behavioral health problems and improving treatment outcomes for people with tuberculosis in India
Funded at Tufts University Boston · NIH-11574759 · Data updated 2026-11-12
A doctor-research team will test a flexible mental health therapy called CETA to help people with tuberculosis who also struggle with depression and unhealthy alcohol use, aiming to improve their TB treatment success.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tufts University Boston NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 18, 2026 |
| Project end | April 30, 2031 |
| Funding year | 2026 |
| Award (this year) | $132,918 |
| NIH project number | 3R01MH137858-01S1 |
| Project ID | NIH-11574759 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with TB who also have depression and/or unhealthy alcohol use and who can be treated in a TB care setting.
✕Less likely to help
Patients without TB or without co-occurring mental health or alcohol problems may not benefit from this approach.
What this research studies
This project adapts a multi-condition therapy so one provider can treat several mental health and behavioral issues that commonly occur with TB. It will be delivered by trained lay health workers and tested to see if it helps patients stick to TB medications and feel better overall. The study builds on prior work showing CETA can address multiple problems at once, and will tailor it for TB care in a real-world setting. Researchers will monitor both mental health outcomes and TB treatment results to understand the overall impact.
Why it matters
Potential benefit: If successful, patients with TB could receive integrated mental health support that improves adherence to treatment and health outcomes.
How similar studies have gone: Previous CETA work reduced multiple mental health issues but has not been implemented within TB care, making this a novel but promising approach.
Where this research is happening
-
Tufts University Boston
Boston, United States Active
Researchers
- Principal investigator: Subbaraman, Ramnath — Tufts University Boston
- Study coordinator: Subbaraman, Ramnath
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.