Smoking cessation support for people with HIV in South Africa
Official title: Evaluating smoking cessation interventions for PWH in South Africa: Efficacy, implementation, and cost-effectiveness.
Funded at Johns Hopkins University · NIH-11419226 · Data updated 2026-11-12
A Johns Hopkins-led effort tests practical, proven smoking-cessation approaches with people living with HIV in South Africa to see if they work well in that setting and are worth expanding.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 15, 2021 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $440,956 |
| NIH project number | 5U01CA261626-06 |
| Project ID | NIH-11419226 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults living with HIV in South Africa who smoke and are eligible for smoking-cessation interventions.
✕Less likely to help
Smokers unaware of their HIV status or those not engaged in HIV care may not directly benefit.
What this research studies
This project aims to optimize a smoking cessation program for people with HIV in South Africa by testing how well the interventions work, how easily they can be put into practice, and whether they are cost-effective. It builds on strategies that have succeeded in other low-resource settings and considers the local TB and cardiovascular risks that smoking adds for people living with HIV. The study will look at real-world delivery in primary care and ART clinics, focusing on implementation and sustainability in addition to efficacy. The findings could inform policy and clinical guidelines to reduce smoking-related health burdens in South Africa and similar contexts.
Why it matters
Potential benefit: If successful, the program could reduce smoking-related illnesses and extend the healthy life span of people living with HIV in South Africa.
How similar studies have gone: Previous studies in other low-resource settings show promise for these interventions, supporting the potential for successful translation to similar populations.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Golub, Jonathan E. — Johns Hopkins University
- Study coordinator: Golub, Jonathan E.
Related research
Other NIH-funded projects on the same topics.
-
Social stress and smoking: why disadvantaged young adults struggle to quit
This grant looks at how daily social stress affects if and when disadvantaged young adults who smoke can quit and stay quit.
-
I-STOP: a mobile health program to help people with HIV quit smoking
A smartphone-based program designed to help people with HIV quit smoking in a sustainable, affordable way.
-
Smoking cessation help for people with HIV in South Africa
A program is being tested to help people living with HIV in South Africa quit smoking in ways that fit low-resource clinics and show good value.
-
Mobile tools to understand how sleep affects quitting smoking
This project uses a smartphone to track sleep and smoking in lower-income adults trying to quit to find how sleep patterns relate to staying smoke-free.
-
Integrated approach to lung screening and quitting for African Americans
A multi-level program aims to boost LDCT lung cancer screening uptake and help African American smokers quit, with support from a comprehensive community-focused plan.
-
Peer-led smoking-cessation program for public housing residents
A peer-led program with eight group sessions plus nicotine replacement therapy is tested on adults living in public housing to help them quit smoking.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.