Remote monitoring and nurse follow-up to manage chemotherapy-induced peripheral neuropathy
Official title: Remote Monitoring of Management of Chemotherapy induced Peripheral Neuropathy
Funded at University of Vermont & St Agric College · NIH-11328854 · Data updated 2026-11-12
A program uses symptom reporting tools with nurse follow-up to reduce and better manage chemotherapy-induced neuropathy for cancer survivors, during and after treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Vermont & St Agric College NIH-funded |
| Lab location | 1 site (Burlington, United States) |
| Project start | May 6, 2021 |
| Project end | April 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $372,282 |
| NIH project number | 5R01CA247517-06 |
| Project ID | NIH-11328854 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with cancer who have or are experiencing chemotherapy-induced peripheral neuropathy and can use phone, app, or web-based reporting.
✕Less likely to help
Patients without CIPN or those unable to use digital symptom reporting tools may see little to no benefit.
What this research studies
This project tests a care model called Symptom Care at Home with NP follow up (SCH-NP) to help people experiencing CIPN during the most painful and disabling times. Patients would report CIPN symptoms via phone, app, or web, and receive proactive nurse practitioner follow-up and a standardized guideline-based care plan. The study will compare SCH-NP to usual care over 12 weeks after chemotherapy to see if CIPN symptoms improve and overall quality of life improves. The goal is to show that proactive, guideline-driven symptom management can reduce CIPN burden and healthcare needs for cancer survivors.
Why it matters
Potential benefit: If successful, patients could experience less CIPN pain and disability and better quality of life during and after chemotherapy.
How similar studies have gone: Prior work showed that symptom reporting with nurse follow-up reduced CIPN symptoms during chemotherapy; this study extends to the post-chemotherapy period with maximal symptoms.
Where this research is happening
-
University of Vermont & St Agric College
Burlington, United States Active
Researchers
- Principal investigator: Kolb, Noah Allan — University of Vermont & St Agric College
- Study coordinator: Kolb, Noah Allan
Related research
Other NIH-funded projects on the same topics.
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Non-invasive, microscopic biomarkers to detect CIPN in chemotherapy patients
This grant aims to develop a non-invasive imaging method to measure nerve changes in patients undergoing chemotherapy to better understand and monitor chemotherapy-induced peripheral neuropathy (CIPN).
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Longitudinal study of how body-sense relates to chemotherapy nerve damage
This study follows people with breast or gastrointestinal cancer and healthy controls to see if brain processing of body sensations contributes to chemotherapy-induced nerve damage.
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A new screen for chemotherapy-related nerve problems in young children
A clinician-scientist at Yale is developing a child-friendly survey to quickly screen for nerve-related side effects from cancer treatment in kids from birth to age 5.
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How the immune system’s CD4+ T cells in women might prevent chemotherapy-related nerve pain
A study in mice explores whether female immune cells in nerve tissue can lessen pain from chemotherapy, with potential implications for preventing CIPN in women.
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Axonal transport and chemotherapy-related nerve pain
This grant studies why certain cancer patients develop painful nerve damage from chemotherapy and explores ways to prevent or treat it.
-
Non-opioid pain relief for chemotherapy-related nerve pain using CART II
A study tests a brain-acting peptide called CART II to help reduce pain from chemotherapy-induced nerve damage without opioids.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.