Reducing chronic leg problems after blood clots
Preventing Post-Thrombotic Syndrome after Deep Vein Thrombosis with Perivascular Anti-Inflammatory Agent Delivery
This study is looking at a new way to help people who have had a blood clot (DVT) avoid developing a painful condition called post-thrombotic syndrome (PTS) by using special treatments that reduce inflammation in the affected blood vessels, so you can feel better and improve your quality of life.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mercator Medsystems, INC. NIH-funded |
| Lab location | 1 site (San Leandro, UNITED STATES) |
| Project ID | NIH-10823041 on NIH RePORTER |
What this research studies
This research focuses on preventing post-thrombotic syndrome (PTS), a painful and debilitating condition that can occur after deep vein thrombosis (DVT). The approach involves delivering anti-inflammatory agents directly to the affected blood vessels to address the underlying inflammation that contributes to PTS. By targeting the inflammation rather than just the blood clot itself, the research aims to improve patient outcomes and quality of life. Patients will be monitored for changes in symptoms and overall health as part of the treatment process.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have been diagnosed with deep vein thrombosis and are at risk of developing post-thrombotic syndrome.
Not a fit: Patients who have not experienced deep vein thrombosis or those with other unrelated chronic conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of post-thrombotic syndrome in patients who have experienced deep vein thrombosis.
How similar studies have performed: While catheter-based therapies have been tested, this approach of directly targeting inflammation with anti-inflammatory agents is novel and has not been extensively studied.
Where this research is happening
San Leandro, UNITED STATES
- Mercator Medsystems, INC. — San Leandro, United States (Active)
Researchers
- Principal investigator: Seward, Kirk — Mercator Medsystems, INC.
- Study coordinator: Seward, Kirk
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.