NIH-funded research R01 grant

Promoting Breastfeeding to Prevent Postpartum Smoking Relapse

Official title: Prevention of Postpartum Smoking Relapse and Related Health Consequences by Breastfeeding Promotion

Funded at State University of New York at Buffalo · NIH-11400074 · Data updated 2026-11-12

A trial tests whether encouraging new mothers to breastfeed helps prevent them from starting to smoke again after giving birth.

More Smoking research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionState University of New York at Buffalo
NIH-funded
Lab location1 site (Amherst, United States)
Project startAugust 25, 2025
Project endJuly 31, 2030
Funding year2026
Award (this year)$683,545
NIH project number5R01HD117113-02
Project IDNIH-11400074 on NIH RePORTER

Who could benefit from this research

Could help

Mothers who smoked before or during pregnancy and are breastfeeding or considering breastfeeding, within the study’s recruitment area.

Less likely to help

Mothers who do not breastfeed or are not able to participate in the program may not benefit.

What this research studies

Many women quit smoking during pregnancy, but lots relapse after delivery. This study tests if boosting breastfeeding support can reduce relapse rates in the first year after birth. Pregnant-to-postpartum participants will be randomized to receive a breastfeeding-promotion program and standard care, with outcomes on smoking status and child health. The goal is to find a practical way to cut postpartum smoking and improve infant well‑being.

Why it matters

Potential benefit: If successful, mothers may stay smoke-free after birth, improving their health and their babies’ health.

How similar studies have gone: Previous work shows breastfeeding and smoking behaviors may be linked, but causal impact requires confirmation; this trial adds new evidence.

Where this research is happening

  • State University of New York at Buffalo
    Amherst, United States
    Active

Researchers

  • Principal investigator: Wen, Xiaozhong — State University of New York at Buffalo
  • Study coordinator: Wen, Xiaozhong

Related research

Other NIH-funded projects on the same topics.

  • Helping new mothers avoid smoking after childbirth

    This project looks at whether adjusting hormone levels can help new mothers stay smoke-free after their baby is born, protecting both mom and child.

    NIH research University of Minnesota · Minneapolis, United States · NIH-11116923

  • Using bupropion to help new mothers avoid smoking relapse after childbirth

    This study is looking at how well bupropion can help women who quit smoking during pregnancy stay smoke-free after having their baby, especially during the tough postpartum period when many might start smoking again.

    NIH research University of Minnesota · Minneapolis, United States · NIH-10889091

  • Using hormone therapy to help new mothers avoid smoking relapse

    This study is looking at how giving new moms a hormone called progesterone might help them avoid smoking again after having a baby, making it easier for them to stay smoke-free and protect their little ones from secondhand smoke.

    NIH research University of Minnesota · Minneapolis, United States · NIH-10861712

  • Social stress and smoking: why disadvantaged young adults struggle to quit

    This grant looks at how daily social stress affects if and when disadvantaged young adults who smoke can quit and stay quit.

    NIH research Medical University of South Carolina · Charleston, United States · NIH-11540695

  • Adaptive treatment for early smoking relapse in adults

    This study tests different paths to help adults who smoke quit again after an early relapse, including trying a different quitting medicine or switching to a safer nicotine product.

    NIH research Medical University of South Carolina · Charleston, United States · NIH-11362332

  • CBT for Insomnia to Help Adults Who Smoke Quit and Sleep Better

    A sleep-focused therapy is tested to help adults who smoke sleep better, feel less negative, and improve their ability to quit smoking.

    NIH research Yale University · New Haven, United States · NIH-11353933

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.