Using bupropion to help new mothers avoid smoking relapse after childbirth

Bupropion for the prevention of postpartum smoking relapse

NIH-funded research University of Minnesota · NIH-10889091

This study is looking at how well bupropion can help women who quit smoking during pregnancy stay smoke-free after having their baby, especially during the tough postpartum period when many might start smoking again.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Minnesota NIH-funded
Lab location1 site (Minneapolis, United States)
Project IDNIH-10889091 on NIH RePORTER

What this research studies

This research investigates the effectiveness of bupropion, a medication commonly used for smoking cessation, in preventing relapse among women who quit smoking during pregnancy. The study focuses on the postpartum period, which is a critical time when many women return to smoking. By addressing factors such as depression and weight concerns that contribute to relapse, the research aims to provide a comprehensive treatment approach. Participants will receive bupropion and be monitored for their smoking habits and overall well-being.

Who could benefit from this research

Good fit: Ideal candidates for this research are women who have successfully quit smoking during pregnancy and are at risk of relapse postpartum.

Not a fit: Patients who have never smoked or those who did not quit smoking during pregnancy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce smoking relapse rates among new mothers, leading to better health outcomes for both mothers and their children.

How similar studies have performed: Previous research has shown that bupropion can effectively aid smoking cessation in the general population, suggesting potential for success in this specific postpartum context.

Where this research is happening

Minneapolis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.