Preventing heart problems after liver transplant in people with high blood pressure
Official title: Avoiding Cardiovascular Complications in Liver Transplantation through Novel Studies (ACCT NOW) in Hypertension
Funded at Ut Southwestern Medical Center · NIH-11345499 · Data updated 2026-11-12
This grant funds a study to understand how best to manage blood pressure in liver transplant patients to reduce heart-related complications.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project start | August 15, 2024 |
| Project end | May 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $709,275 |
| NIH project number | 5R01HL171207-03 |
| Project ID | NIH-11345499 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults who have undergone liver transplantation and are at risk for high blood pressure or cardiovascular events.
✕Less likely to help
Patients without high blood pressure or cardiovascular risk may not see direct benefits from altered blood pressure strategies.
What this research studies
This project follows liver transplant recipients to track blood pressure, heart-related biomarkers, and kidney and brain health over several years. Researchers will compare different blood pressure targets and treatment strategies in a large, multi-center group to see what helps most without harming the liver or kidneys. Participants will provide home blood pressure data, blood samples, and information on health outcomes like heart events and cognitive function. The study uses precision medicine ideas to tailor treatment based on individual biomarker levels. Results could guide doctors on safer, more effective blood pressure care after transplant.
Why it matters
Potential benefit: If successful, patients could receive more personalized and safer blood pressure management after liver transplantation, potentially reducing heart problems and preserving organ function.
How similar studies have gone: Previous research suggests blood pressure management matters, but this study aims to personalize targets using biomarkers in transplant patients.
Where this research is happening
-
Ut Southwestern Medical Center
Dallas, United States Active
Researchers
- Principal investigator: Vanwagner, Lisa B — Ut Southwestern Medical Center
- Study coordinator: Vanwagner, Lisa B
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.