Improving heart health in liver transplant patients with high blood pressure
Official title: Avoiding Cardiovascular Complications in Liver Transplantation through Novel Studies (ACCT NOW) in Hypertension
Funded at Ut Southwestern Medical Center · NIH-11164625 · Data updated 2026-11-12
This study is looking at the best ways to help liver transplant patients manage their high blood pressure to keep their hearts healthy, and it will track their progress over two years to find the most effective treatments just for them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project start | August 15, 2024 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $727,222 |
| NIH project number | 5R01HL171207-02 |
| Project ID | NIH-11164625 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have received a liver transplant and are experiencing high blood pressure.
✕Less likely to help
Patients who have not undergone liver transplantation or do not have hypertension may not benefit from this research.
What this research studies
This research investigates how to better manage high blood pressure in liver transplant recipients to prevent cardiovascular complications. It aims to identify the best treatment approaches by measuring blood pressure, cardiac biomarkers, and various health outcomes over a two-year period. By focusing on precision medicine, the study seeks to tailor hypertension management based on individual patient needs, potentially improving overall health and recovery after transplantation.
Why it matters
Potential benefit: If successful, this research could lead to more effective blood pressure management strategies that reduce the risk of cardiovascular events in liver transplant patients.
How similar studies have gone: Previous research has shown that targeted approaches to managing hypertension can significantly improve outcomes in high-risk populations, suggesting potential success for this study.
Where this research is happening
-
Ut Southwestern Medical Center
Dallas, United States Active
Researchers
- Principal investigator: Vanwagner, Lisa B — Ut Southwestern Medical Center
- Study coordinator: Vanwagner, Lisa B
Related research
Other NIH-funded projects on the same topics.
-
Preventing heart problems after liver transplant in people with high blood pressure
This grant funds a study to understand how best to manage blood pressure in liver transplant patients to reduce heart-related complications.
-
HEARTS hypertension and diabetes care in Guatemala
This grant tests how well the HEARTS primary care model works in Guatemala to improve blood pressure and blood sugar control for patients.
-
Integrated Heart Health: A HEARTS-based approach to hypertension and diabetes in Guatemala
A study tests a team-based, stepwise care model to improve blood pressure and blood sugar control for people with both hypertension and diabetes in Guatemala.
-
Coaching and Navigation by Community Health Workers via Telehealth for High-Risk Hypertension
A program using telehealth and community health workers to help adults with severe hypertension connect to primary care and follow practical, heart-healthy lifestyle tips.
-
Community Health Worker–Led Hypertension Prevention and Control in Nepal
A community health worker–driven approach in Nepal aims to prevent and control high blood pressure among adults by bringing education and care directly to communities and homes.
-
Community health worker-led hypertension prevention and control in Nepal
A community health worker–led program in Nepal aims to help adults prevent and better control high blood pressure through home visits, education, and ongoing support.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.