NIH-funded research R01 grant

Community health worker-led hypertension prevention and control in Nepal

Official title: Community Health Worker Led Hypertension Prevention and Control (CHPC) in Nepal: An Implementation Trial

Funded at Yale University · NIH-11631224 · Data updated 2026-11-12

A community health worker–led program in Nepal aims to help adults prevent and better control high blood pressure through home visits, education, and ongoing support.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University
NIH-funded
Lab location1 site (New Haven, United States)
Project startSeptember 1, 2023
Project endJune 30, 2028
Funding year2026
Award (this year)$96,960
NIH project number3R01HL169421-04S1
Project IDNIH-11631224 on NIH RePORTER

Who could benefit from this research

Could help

Adults 21 years and older with hypertension or at risk, living in targeted communities in Nepal.

Less likely to help

Patients not engaged by CHWs or outside the program’s service areas may see limited benefit.

What this research studies

This project partners with local communities in Nepal to shift hypertension care tasks to trained community health workers who will engage people at home and in clinics. CHWs will have extended education and follow-up with adults to improve awareness, screen for high blood pressure, support treatment adherence, and promote healthy lifestyle changes. The plan includes implementing and evaluating a task-shifting approach within the existing health system to address multi-level barriers to care. The study will measure changes in BP control, treatment uptake, and patient knowledge over time. Results could guide scalable strategies to reduce cardiovascular risk in low-resource settings.

Why it matters

Potential benefit: If successful, patients with hypertension in Nepal could experience better blood pressure control and lower risk of heart disease and stroke.

How similar studies have gone: Similar CHW-led approaches have shown promise in improving BP management in resource-limited settings, though contexts vary.

Where this research is happening

  • Yale University
    New Haven, United States
    Active

Researchers

  • Principal investigator: Spiegelman, Donna L — Yale University
  • Study coordinator: Spiegelman, Donna L

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.