NIH-funded research R01 grant

Community Health Worker–Led Hypertension Prevention and Control in Nepal

Official title: Community Health Worker Led Hypertension Prevention and Control (CHPC) in Nepal: An Implementation Trial

Funded at Yale University · NIH-11631225 · Data updated 2026-11-12

A community health worker–driven approach in Nepal aims to prevent and control high blood pressure among adults by bringing education and care directly to communities and homes.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University
NIH-funded
Lab location1 site (New Haven, United States)
Project startSeptember 1, 2023
Project endJune 30, 2028
Funding year2026
Award (this year)$231,529
NIH project number3R01HL169421-04S2
Project IDNIH-11631225 on NIH RePORTER

Who could benefit from this research

Could help

Adults 21 years and older in Nepal who have hypertension or are at risk and are reachable through community health workers.

Less likely to help

Individuals without hypertension or those unable to engage with CHW visits may derive limited or no direct benefit.

What this research studies

This project partners with community health workers in Nepal to deliver intensified education, home visits, and support to adults with hypertension or at risk, using a task-shifting model to improve detection, treatment, and BP control. It builds on the Nepal PEN program to address barriers at individual, interpersonal, community, and organizational levels that hinder effective hypertension care. The study will implement and evaluate how CHWs, with structured training and home-based engagement, impact BP outcomes and adherence to treatment in real-world health facilities. Participants will include Nepalese adults aged 21 and older who are screened for hypertension and receive ongoing CHW-led support. The findings could inform scalable strategies to reduce cardiovascular risk in similar low-resource settings.

Why it matters

Potential benefit: If successful, the approach could help more people manage high blood pressure, lowering the risk of heart attacks and strokes in Nepal and similar settings.

How similar studies have gone: Prior work suggests community health workers can improve chronic disease management, though results vary by setting and implementation.

Where this research is happening

  • Yale University
    New Haven, United States
    Active

Researchers

  • Principal investigator: Spiegelman, Donna L — Yale University
  • Study coordinator: Spiegelman, Donna L

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.