Prediction of alcohol problems and PTSD after trauma in teens
Official title: Prediction of Alcohol Use Disorder and PTSD After Trauma in Adolescents
Funded at University of Texas at Austin · NIH-11391105 · Data updated 2026-11-12
Teens who experience acute trauma are studied to see if certain biological signals can predict who might develop Alcohol Use Disorder or PTSD.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas at Austin NIH-funded |
| Lab location | 1 site (Austin, United States) |
| Project start | September 5, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $859,075 |
| NIH project number | 5R01AA029090-05 |
| Project ID | NIH-11391105 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adolescents aged 12-20 who have recently experienced acute trauma and present to participating Texas sites.
✕Less likely to help
Teens without acute trauma or those not at risk may not benefit from the predictive markers identified by this study.
What this research studies
We will enroll 500 adolescents who recently experienced acute trauma and gather biological samples, physiological data, and psychosocial information in Texas from emergency departments and clinics. Using advanced analytics and machine learning, researchers will look for genomic, epigenomic, inflammatory, and psychophysiological markers that could signal risk for AUD and PTSD. The study is designed to identify early-risk indicators so that clinicians could intervene sooner and tailor support for youths at highest risk.
Why it matters
Potential benefit: If successful, the findings could lead to earlier, targeted prevention efforts for teens at risk of AUD and PTSD after trauma.
How similar studies have gone: Previous adult studies show linked risk factors; this project explores adolescent-specific biomarkers which are less established.
Where this research is happening
-
University of Texas at Austin
Austin, United States Active
Researchers
- Principal investigator: Nemeroff, Charles B — University of Texas at Austin
- Study coordinator: Nemeroff, Charles B
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.