Finding brain proteins linked to PTSD and alcohol use disorder
Identifying Novel Brain Proteins Contributing to PTSD and Alcohol Use Disorder
This study is looking at how certain proteins in the brain might be linked to PTSD and alcohol use problems in U.S. Veterans, with the hope of finding new treatments that can help those dealing with these challenges.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA Northern California Health Care Sys NIH-funded |
| Lab location | 1 site (Mather, United States) |
| Project ID | NIH-11171348 on NIH RePORTER |
What this research studies
This research investigates the connection between brain proteins and the development of post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD), particularly in U.S. Veterans. By analyzing genetic data from large studies, the research aims to identify specific proteins that may contribute to these disorders, which often occur together and complicate treatment. The study employs advanced genetic analysis techniques to pinpoint which genetic variations are truly responsible for these conditions, potentially leading to new treatment options. Patients may benefit from the development of targeted therapies that address the underlying biological mechanisms of PTSD and AUD.
Who could benefit from this research
Good fit: Ideal candidates for this research are U.S. Veterans experiencing PTSD, alcohol use disorder, or both.
Not a fit: Patients without PTSD or alcohol use disorder, or those who do not have a genetic predisposition to these conditions, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new, more effective treatments for PTSD and alcohol use disorder.
How similar studies have performed: Previous research has shown promise in identifying genetic factors related to PTSD and AUD, suggesting that this approach may yield valuable insights.
Where this research is happening
Mather, United States
- VA Northern California Health Care Sys — Mather, United States (Active)
Researchers
- Principal investigator: Wingo, Aliza Pham — VA Northern California Health Care Sys
- Study coordinator: Wingo, Aliza Pham
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.