Predicting Risk and Treatment Effects in Cardiogenic Shock after Heart Attack
Official title: Application of Modern Methods to Predict Risk and Estimate Treatment Effectiveness in Cardiogenic Shock
Funded at Beth Israel Deaconess Medical Center · NIH-11397533 · Data updated 2026-11-12
This grant backs a patient-focused effort to use modern methods to understand how to best use life-saving devices in people who have a heart attack with severe heart pump failure.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 19, 2025 |
| Project end | May 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $765,316 |
| NIH project number | 5R01HL180887-02 |
| Project ID | NIH-11397533 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients who have had an acute myocardial infarction complicated by cardiogenic shock and are candidates for mechanical circulatory support devices.
✕Less likely to help
Patients without cardiogenic shock or without a heart attack context are not the target for this study.
What this research studies
Researchers will combine data from recent trials with real-world registries to see which mechanical support devices work best for people with heart attacks complicated by cardiogenic shock. They will use advanced statistical methods to determine how trial results apply to today’s patients and what factors influence outcomes. The project aims to clarify when to use specific devices and how best to apply trial evidence in everyday cardiology practice. This could help clinicians tailor treatments to improve survival and recovery for affected patients.
Why it matters
Potential benefit: If successful, the work could lead to clearer, personalized guidelines for using mechanical support devices in cardiogenic shock, potentially improving survival and quality of life for heart attack patients with this complication.
How similar studies have gone: Previous randomized trials and contemporary registries have shown mixed results, and this project seeks to illuminate how trial findings translate to current practice, which is an evolving area.
Where this research is happening
-
Beth Israel Deaconess Medical Center
Boston, United States Active
Researchers
- Principal investigator: Yeh, Robert — Beth Israel Deaconess Medical Center
- Study coordinator: Yeh, Robert
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.