How pancreas changes relate to type 2 diabetes, pancreatitis, and pancreatic cancer
The Exocrine and Endocrine Pancreas in Type 2 Diabetes, Pancreatitis and Cancer
['FUNDING_U01'] · MAYO CLINIC ROCHESTER · NIH-11219603
This multi-center effort looks at pancreas changes in adults with chronic or recurrent pancreatitis, type 2 diabetes, or pancreatic cancer to improve diagnosis and care.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MAYO CLINIC ROCHESTER (nih funded) |
| Locations | 1 site (ROCHESTER, UNITED STATES) |
| Trial ID | NIH-11219603 on ClinicalTrials.gov |
What this research studies
If you take part, the consortium will follow adults with acute recurrent or chronic pancreatitis, type 2 diabetes, or pancreatic cancer over time and collect blood and other biospecimens. Mayo Clinic Rochester is a major recruitment site and will continue follow-up of participants from prior consortium cycles while adding new patients. The program includes linked studies on biomarkers, saliva testing, and two planned clinical trials (one related to diabetes and one to smoking and chronic pancreatitis). You may be asked for periodic clinic visits, sample donations, and to share health information for long-term follow-up.
Who could benefit from this research
Good fit: Adults (typically age 21 and older) with acute recurrent pancreatitis, chronic pancreatitis, type 2 diabetes, or pancreatic cancer who can attend follow-up visits and provide biospecimens are the ideal candidates.
Not a fit: Children, people without pancreatitis or diabetes, or those unable to travel to participating centers for visits and sample collection are unlikely to benefit directly from this effort.
Why it matters
Potential benefit: Better understanding of how pancreas changes link these conditions could lead to earlier diagnosis, targeted treatments, and prevention strategies for patients.
How similar studies have performed: The CPDPC consortium has run prior multi-center cycles that successfully recruited patients and produced biomarker and ancillary-study data, though treatment trials in this area are still evolving.
Where this research is happening
ROCHESTER, UNITED STATES
- MAYO CLINIC ROCHESTER — ROCHESTER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: VEGE, SANTHI SWAROOP — MAYO CLINIC ROCHESTER
- Study coordinator: VEGE, SANTHI SWAROOP
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Adult-Onset Diabetes Mellitus