How pancreas changes relate to type 2 diabetes, pancreatitis, and pancreatic cancer
Official title: The Exocrine and Endocrine Pancreas in Type 2 Diabetes, Pancreatitis and Cancer
Funded at Mayo Clinic Rochester · NIH-11219603 · Data updated 2026-11-12
This multi-center effort looks at pancreas changes in adults with chronic or recurrent pancreatitis, type 2 diabetes, or pancreatic cancer to improve diagnosis and care.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | September 28, 2015 |
| Project end | June 30, 2030 |
| Funding year | 2025 |
| Award (this year) | $512,400 |
| NIH project number | 2U01DK108288-11 |
| Project ID | NIH-11219603 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults (typically age 21 and older) with acute recurrent pancreatitis, chronic pancreatitis, type 2 diabetes, or pancreatic cancer who can attend follow-up visits and provide biospecimens are the ideal candidates.
✕Less likely to help
Children, people without pancreatitis or diabetes, or those unable to travel to participating centers for visits and sample collection are unlikely to benefit directly from this effort.
What this research studies
If you take part, the consortium will follow adults with acute recurrent or chronic pancreatitis, type 2 diabetes, or pancreatic cancer over time and collect blood and other biospecimens. Mayo Clinic Rochester is a major recruitment site and will continue follow-up of participants from prior consortium cycles while adding new patients. The program includes linked studies on biomarkers, saliva testing, and two planned clinical trials (one related to diabetes and one to smoking and chronic pancreatitis). You may be asked for periodic clinic visits, sample donations, and to share health information for long-term follow-up.
Why it matters
Potential benefit: Better understanding of how pancreas changes link these conditions could lead to earlier diagnosis, targeted treatments, and prevention strategies for patients.
How similar studies have gone: The CPDPC consortium has run prior multi-center cycles that successfully recruited patients and produced biomarker and ancillary-study data, though treatment trials in this area are still evolving.
Where this research is happening
-
Mayo Clinic Rochester
Rochester, United States Active
Researchers
- Principal investigator: Vege, Santhi Swaroop — Mayo Clinic Rochester
- Study coordinator: Vege, Santhi Swaroop
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.