Neural signals linked to recovery from aphasia after stroke
Official title: Neural Correlates of Recovery from Aphasia After Stroke
Funded at Vanderbilt University Medical Center · NIH-11565238 · Data updated 2026-11-12
This grant follows people who recently had a stroke and aphasia to understand why some recover language abilities better than others.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | June 1, 2014 |
| Project end | June 30, 2030 |
| Funding year | 2026 |
| Award (this year) | $129,987 |
| NIH project number | 3R01DC013270-12S1 |
| Project ID | NIH-11565238 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with aphasia following an acute stroke who are enrolled within the first weeks to months after the event.
✕Less likely to help
People without aphasia or without a history of stroke are unlikely to benefit.
What this research studies
The research tracks adults with aphasia after stroke over the first year to map how speech and language improve. It uses brain imaging and behavioral tests to find patterns that predict recovery. The study builds on a large, existing database and will enroll 240 new participants to expand understanding and guide future care. Findings could help tailor therapies based on brain imaging and individual recovery paths.
Why it matters
Potential benefit: Better prediction of who will recover language skills and more personalized rehabilitation plans.
How similar studies have gone: Previous work has mapped recovery trajectories and identified predictors, supporting continued progress in this area.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: De Riesthal, Michael R — Vanderbilt University Medical Center
- Study coordinator: De Riesthal, Michael R
Related research
Other NIH-funded projects on the same topics.
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Computational modeling of language in bilingual adults after stroke and with neurodegenerative conditions
A computer-based study will model how bilingual Spanish-English speakers experience language changes after stroke and with neurodegenerative disorders, to inform better care for affected patients.
-
Restoring speech with a brain implant for stroke-related aphasia
A study at UC Davis aims to help people who have language trouble after a stroke by using a tiny brain implant to turn brain signals into spoken words.
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Predicting language recovery after stroke using AI
A new AI-based project uses brain scans and personal data to forecast how aphasia may progress after a stroke, with the goal of guiding personalized treatment.
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Neural signals of getting speech back after stroke
This grant studies how the brain changes as people recover speech after a stroke, to help predict and improve language recovery.
-
How the brain recovers language after a stroke
This research follows people with aphasia after stroke to find brain and behavior signs that predict who will regain speech and language.
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Electrical Field Guided TMS and Constraint Induced Language Therapy for Subacute Post-Stroke Aphasia
This study tests a targeted brain stimulation plus speech therapy approach to help people with language loss after a recent stroke.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.