Computational modeling of language in bilingual adults after stroke and with neurodegenerative conditions
Official title: Computational modeling of language impairment and control in bilingual individuals with post-stroke aphasia and neurodegenerative disorders
Funded at Boston University (Charles River Campus) · NIH-11402621 · Data updated 2026-11-12
A computer-based study will model how bilingual Spanish-English speakers experience language changes after stroke and with neurodegenerative disorders, to inform better care for affected patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University (Charles River Campus) NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 4, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $623,563 |
| NIH project number | 5R01DC020653-04 |
| Project ID | NIH-11402621 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults who are bilingual Spanish-English speakers affected by stroke or neurodegenerative disease, along with aging individuals for comparisons.
✕Less likely to help
Individuals without bilingual language use or those not affected by stroke or neurodegenerative conditions may not directly benefit.
What this research studies
This project uses computational simulations to map how bilingual language processing changes with stroke and aging. It aims to describe how people switch between languages and how impairment and decline occur over time. The work focuses on Spanish-English speakers in the adult population to understand variations in language outcomes. Results could help clinicians tailor speech-language therapy and communication strategies for bilingual patients. The study will analyze cross-sectional and longitudinal data to capture the diverse ways bilingualism interacts with brain diseases.
Why it matters
Potential benefit: If successful, findings could improve diagnosis, therapy planning, and personalized communication support for bilingual patients with stroke or dementia.
How similar studies have gone: Previous research shows promising insights from computational approaches, but this project explores a specific bilingual population with stroke and neurodegeneration.
Where this research is happening
-
Boston University (Charles River Campus)
Boston, United States Active
Researchers
- Principal investigator: Kiran, Swathi — Boston University (Charles River Campus)
- Study coordinator: Kiran, Swathi
Related research
Other NIH-funded projects on the same topics.
-
Neural signals linked to recovery from aphasia after stroke
This grant follows people who recently had a stroke and aphasia to understand why some recover language abilities better than others.
-
Restoring speech with a brain implant for stroke-related aphasia
A study at UC Davis aims to help people who have language trouble after a stroke by using a tiny brain implant to turn brain signals into spoken words.
-
Predicting language recovery after stroke using AI
A new AI-based project uses brain scans and personal data to forecast how aphasia may progress after a stroke, with the goal of guiding personalized treatment.
-
Neural signals of getting speech back after stroke
This grant studies how the brain changes as people recover speech after a stroke, to help predict and improve language recovery.
-
How the brain recovers language after a stroke
This research follows people with aphasia after stroke to find brain and behavior signs that predict who will regain speech and language.
-
Electrical Field Guided TMS and Constraint Induced Language Therapy for Subacute Post-Stroke Aphasia
This study tests a targeted brain stimulation plus speech therapy approach to help people with language loss after a recent stroke.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.