Multi-omics study of diabetes, kidney disease, and environment in diverse adults
Official title: Multi-Omics at the Intersections of Environment, Diabetes, and Kidney Disease: A Multi-Omics for Health and Disease Study Site
Funded at University of Illinois at Chicago · NIH-11388620 · Data updated 2026-11-12
Researchers are building a diverse group of adults to learn how environment and biology together affect diabetes and kidney disease, with hopes to improve care for people like them.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Chicago NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project start | September 12, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $737,780 |
| NIH project number | 5U01HG013275-04 |
| Project ID | NIH-11388620 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults (21+) from diverse racial/ethnic backgrounds, including those with diabetes and/or kidney disease, who are willing to provide samples and health information.
✕Less likely to help
People who do not have diabetes or kidney disease, or those unable to participate in long-term multi-omics data collection, may see little direct benefit.
What this research studies
This project creates a study site with 300 adults from diverse racial and ethnic backgrounds, including 200 with diabetes (half with kidney disease) and 100 healthy controls. It will collect multi-omics data alongside environmental exposure information to understand how social and environmental factors influence kidney disease progression in diabetes. The study will collaborate with a larger multi-omics consortium to develop findings that can be applied to real-world care. Participants will be involved through sample collection and health data sharing, with efforts to ensure meaningful representation from Black and Hispanic communities.
Why it matters
Potential benefit: If successful, the work could lead to personalized prevention and treatment strategies for diabetic kidney disease, particularly in underserved populations.
How similar studies have gone: Prior multi-omics studies have shown that integrating environmental data can reveal mechanisms underlying disease disparities, though this project is focused on DKD in diverse populations.
Where this research is happening
-
University of Illinois at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Kelly, Tanika Nicole — University of Illinois at Chicago
- Study coordinator: Kelly, Tanika Nicole
Related research
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A medical research project is testing whether a specific protein fragment in the blood harms both the pancreas and kidneys, which could lead to future therapies for adults with diabetes and kidney disease.
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This project uses modern kidney biopsies and advanced molecular tests to look for energy and oxygen problems in the kidneys of adults with type 1 diabetes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.