NIH-funded research R01 grant

Mitigating Dry Eye Symptoms by Improving Indoor Air Quality

Official title: Mitigating the Dry Eye Disease Burden by Improving Indoor Air Quality

Funded at University of Miami School of Medicine · NIH-11344220 · Data updated 2026-11-12

Aimed at adults with dry eye symptoms, this study tests a low-cost, multi-faceted plan to improve indoor air and reduce eye discomfort.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Miami School of Medicine
NIH-funded
Lab location1 site (Coral Gables, United States)
Project startAugust 1, 2026
Project endMay 31, 2031
Funding year2026
Award (this year)$1,182,523
NIH project number1R01EY038959-01
Project IDNIH-11344220 on NIH RePORTER

Who could benefit from this research

Could help

Adults with dry eye symptoms who live in indoor environments and are willing to participate in a crossover trial.

Less likely to help

Individuals without dry eye symptoms or those not spending significant time indoors may not benefit.

What this research studies

If you have dry eye disease and spend a lot of time indoors, this study will test a simple, affordable program to reduce exposure to indoor pollutants and other stressors. Participants will be adults with dry eye symptoms, enrolled in a randomized, crossover design over nine months while living in the Miami area. The researchers will compare two intervention approaches to see which best eases symptoms and lowers healthcare costs. By focusing on real-world indoor environments and multiple air-related factors, the study seeks practical ways to help people feel better at home or work.

Why it matters

Potential benefit: Could reduce dry eye symptoms and related healthcare costs by improving indoor air quality.

How similar studies have gone: Previous work suggests indoor air quality affects dry eye symptoms, but results for multimodal interventions are still being explored.

Where this research is happening

  • University of Miami School of Medicine
    Coral Gables, United States
    Active

Researchers

  • Principal investigator: Kumar, Naresh — University of Miami School of Medicine
  • Study coordinator: Kumar, Naresh

Related research

Other NIH-funded projects on the same topics.

  • Stabilizing the tear film to relieve evaporative dry eye

    This project tests new ways to stabilize the tear film in people with evaporative dry eye, with the goal of longer-lasting comfort.

    NIH research Michigan State University · East Lansing, United States · NIH-11641969

  • A new way to understand evaporative dry eye

    Researchers are building a lab model to better understand why people develop evaporative dry eye so treatments can be improved.

    NIH research Michigan State University · East Lansing, United States · NIH-11398342

  • Tear microRNA patterns in women and men with dry eye

    Researchers will look at tiny RNA molecules in tear fluid from people with dry eye to find patterns linked to sex and race.

    NIH research Augusta University · Augusta, United States · NIH-11311871

  • Immune causes of chronic dry eye

    This work looks at how certain immune cells make dry eye persist in adults and aims to point toward better, longer-lasting treatments.

    NIH research Schepens Eye Research Institute · Boston, United States · NIH-11237037

  • A new type of plug to help relieve dry eye symptoms

    This study is working on a new type of eye plug that can help make life easier for people with dry eyes by using special materials that adjust to their needs, aiming to provide more comfort and better results than current treatments.

    NIH research Aesculatech, INC. · Los Angeles, UNITED STATES · NIH-11216481

  • Preventing dry eye disease and age-related Meibomian gland dysfunction

    This study is looking at how changing the support structure around eye glands might help prevent dry eye and related issues as we age, and it aims to find new ways to help people who struggle with dry eyes.

    NIH research University of Houston · Houston, United States · NIH-11160450

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.