A new type of plug to help relieve dry eye symptoms

Humidifeye Plug for Dry Eye Disease

['FUNDING_SBIR_2'] · AESCULATECH, INC. · NIH-11216481

This study is working on a new type of eye plug that can help make life easier for people with dry eyes by using special materials that adjust to their needs, aiming to provide more comfort and better results than current treatments.

Quick facts

Phase['FUNDING_SBIR_2']
Study typeNih_funding
SexAll
SponsorAESCULATECH, INC. (nih funded)
Locations1 site (Los Angeles, UNITED STATES)
Trial IDNIH-11216481 on ClinicalTrials.gov

What this research studies

This research focuses on developing a novel punctal plug designed to alleviate symptoms of Dry Eye Disease (DED) using advanced hydrogels that respond to environmental changes. The goal is to create a patient-adaptable device that offers better comfort and effectiveness compared to existing treatments, which often have limitations such as discomfort and poor compliance. By utilizing materials that have been shown to be effective in biomedical applications, the research aims to provide a long-term solution for patients suffering from DED. The project addresses a significant healthcare burden, particularly as the prevalence of dry eye increases with factors like aging and increased screen time.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Dry Eye Disease, particularly those who have not found relief with current treatment options.

Not a fit: Patients who do not have Dry Eye Disease or those who are allergic to the materials used in the plugs may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide patients with a more effective and comfortable treatment option for managing dry eye symptoms.

How similar studies have performed: Previous research has shown promise in using hydrogels for biomedical applications, but this specific approach to long-term medical inserts is novel.

Where this research is happening

Los Angeles, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.