NIH-funded research R01 grant

Mindfulness for mood and heart health during pregnancy

Official title: Mechanisms of Mindfulness for Improving Mood and Cardiovascular Health During the Perinatal Period

Funded at University of Pittsburgh at Pittsburgh · NIH-11294004 · Data updated 2026-11-12

A mindfulness-based program for pregnant and postpartum people to help mood and heart health during the perinatal period.

More Cardiovascular Health research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh
NIH-funded
Lab location1 site (Pittsburgh, United States)
Project startSeptember 4, 2026
Project endAugust 31, 2031
Funding year2026
Award (this year)$780,247
NIH project number1R01HL178654-01A1
Project IDNIH-11294004 on NIH RePORTER

Who could benefit from this research

Could help

Pregnant or recently postpartal individuals at risk for antenatal depression who are able to participate in mindfulness training sessions.

Less likely to help

Individuals without antenatal depression or those unable to participate in mindfulness sessions may see limited or no benefit.

What this research studies

This project tests whether mindfulness training can help reduce depression and improve cardiovascular risk factors in pregnant and postpartum individuals. It uses a parallel design randomized controlled trial to examine mental and physiological pathways that link mood and heart health during pregnancy and after birth. If successful, the study could point to a non-drug approach to protect both maternal mental health and cardiovascular outcomes in the perinatal period.

Why it matters

Potential benefit: If successful, participants may experience better mood and lower cardiovascular risk during and after pregnancy.

How similar studies have gone: Prior research suggests mindfulness can improve mood and some health risk factors, but mechanistic pathways in pregnancy are not yet proven.

Where this research is happening

  • University of Pittsburgh at Pittsburgh
    Pittsburgh, United States
    Active

Researchers

  • Principal investigator: Levine, Michele D — University of Pittsburgh at Pittsburgh
  • Study coordinator: Levine, Michele D

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.