NIH-funded research R01 grant

Understanding how mindfulness can help youth at risk for mood disorders

Official title: Neurobehavioral Targets of Mindfulness in Youth At Risk for Mood Disorders

Funded at University of Pittsburgh at Pittsburgh · NIH-11035159 · Data updated 2026-11-12

This study is looking at how mindfulness practices can help young people who are at risk for mood disorders by improving their emotional control and mood, and it aims to find out who might benefit the most from these techniques.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh
NIH-funded
Lab location1 site (Pittsburgh, United States)
Project startApril 21, 2022
Project endFebruary 28, 2027
Funding year2025
Award (this year)$660,273
NIH project number5R01MH127021-04
Project IDNIH-11035159 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adolescents aged 12-20 who exhibit mood lability and have a familial risk for mood disorders.

Less likely to help

Patients who do not exhibit mood lability or do not have a family history of mood disorders may not benefit from this research.

What this research studies

This research investigates the effects of mindfulness-based interventions (MBIs) on mood lability in youth who are at risk for mood disorders. It aims to understand the neural and behavioral mechanisms behind how mindfulness can improve emotional regulation and decrease mood symptoms. By focusing on adolescents, a critical period for mood disorder onset, the study seeks to identify which individuals may benefit most from these interventions. The research will utilize various assessments to measure changes in mood and brain connectivity associated with mindfulness practices.

Why it matters

Potential benefit: If successful, this research could lead to effective mindfulness-based strategies that help reduce mood swings and improve emotional well-being in at-risk youth.

How similar studies have gone: Previous research has shown that mindfulness-based interventions can effectively reduce mood symptoms in youth, indicating a promising approach for this population.

Where this research is happening

  • University of Pittsburgh at Pittsburgh
    Pittsburgh, United States
    Active

Researchers

  • Principal investigator: Hafeman, Danella Marie — University of Pittsburgh at Pittsburgh
  • Study coordinator: Hafeman, Danella Marie

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.