Metabolomics clocks: a new way to study aging mechanisms
Official title: Metabolomics clocks as a tool to explore mechanisms of aging
Funded at Tufts University Boston · NIH-11384842 · Data updated 2026-11-12
A patient-facing look at how tiny molecules in the body could help us understand why aging happens and how it links to health and disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tufts University Boston NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 30, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $633,880 |
| NIH project number | 5R01AG082696-03 |
| Project ID | NIH-11384842 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults interested in aging research or who want to learn how metabolic markers relate to aging may be eligible for associated future studies or trials.
✕Less likely to help
This particular grant is a basic-science project; it may not immediately lead to treatments for individuals.
What this research studies
This project uses metabolite profiles to study aging and its related health changes, building on work that links metabolites to aging in model organisms and humans. By looking at metabolome clocks, researchers aim to uncover how biological processes drive aging and identify targets that could improve health as we age. The study will leverage established animal models and human data to explore mechanisms behind aging markers, with the goal of translating findings into ways to monitor and potentially influence aging-related health. People may hear about how metabolic signals relate to aging and how this research could pave the way for future biomarkers or interventions.
Why it matters
Potential benefit: If successful, this research could identify new metabolic markers of aging that help predict health risks and guide personalized care in aging populations.
How similar studies have gone: Previous work in model systems has shown metabolite clocks can relate to aging traits and interventions.
Where this research is happening
-
Tufts University Boston
Boston, United States Active
Researchers
- Principal investigator: Promislow, Daniel Edward — Tufts University Boston
- Study coordinator: Promislow, Daniel Edward
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.