Mapping oxygen consumption in the brain for stroke evaluation
Official title: Quantitative Cerebral Oxygen Metabolic Imaging of Acute Ischemic Stroke
Funded at Weill Medical Coll of Cornell Univ · NIH-10990819 · Data updated 2026-11-12
This study is testing a new MRI method to measure how much oxygen your brain is using after a stroke, which can help doctors understand how much of your brain is still healthy and make better treatment choices for you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $666,530 |
| NIH project number | 1R01NS135205-01A1 |
| Project ID | NIH-10990819 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have recently experienced an acute ischemic stroke.
✕Less likely to help
Patients with non-ischemic strokes or those who are not currently experiencing an acute stroke may not benefit from this research.
What this research studies
This research aims to create a new MRI-based method for measuring the brain's oxygen consumption in patients who have suffered an acute ischemic stroke. By accurately mapping cerebral metabolic rate of oxygen consumption (CMRO2), the study seeks to determine the viability of brain tissue affected by ischemia, which is crucial for making informed treatment decisions. The approach involves using advanced imaging techniques to assess blood flow and oxygen extraction in the brain, potentially providing a more reliable assessment than current methods. This could lead to better management of stroke patients and improved outcomes.
Why it matters
Potential benefit: If successful, this research could lead to more accurate assessments of brain tissue viability in stroke patients, enabling timely and effective treatment.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for stroke evaluation, but this specific MRI-based approach is relatively novel.
Where this research is happening
-
Weill Medical Coll of Cornell Univ
New York, United States Active
Researchers
- Principal investigator: Wang, Yi — Weill Medical Coll of Cornell Univ
- Study coordinator: Wang, Yi
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This grant looks at how the body’s internal clock might influence how well stroke patients respond to clot-busting or clot-removal treatments.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.