Liver cancer prevention and care in Uganda using HIV clinic resources
Official title: Leveraging HIV care infrastructure for implementation of context-adapted liver cancer comprehensive control strategies in Uganda: The LC3 Study
Funded at Johns Hopkins University · NIH-11413342 · Data updated 2026-11-12
A project to bring proven liver cancer prevention and care steps into HIV clinics in Uganda to reduce liver cancer deaths.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 3, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $333,963 |
| NIH project number | 5U01CA275117-03 |
| Project ID | NIH-11413342 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults living with HIV in Uganda, particularly in regions with high HBV and liver cancer burden, who participate in HIV care settings.
✕Less likely to help
Patients outside HIV care settings or in regions without capacity to implement the LC3 package may not benefit.
What this research studies
This project builds on a long-standing collaboration between Makerere University and Johns Hopkins to bring HBV and HIV care together in Uganda. It plans to adapt and implement a bundle of liver cancer prevention and treatment strategies within existing HIV care settings, using real-world clinical data and local patient needs. The work will combine diagnostics, birth-dose vaccination efforts, and streamlined treatment pathways in multiple Ugandan regions. The goal is to help people living with HIV access timely HBV-related prevention and liver cancer care within familiar clinic environments.
Why it matters
Potential benefit: If successful, the package could reduce liver cancer risk among people with HIV in Uganda by improving screening, vaccination, and treatment access.
How similar studies have gone: Previous implementation efforts showed that integrating HBV services into HIV care is feasible and can improve care delivery in similar settings.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Kirk, Gregory D — Johns Hopkins University
- Study coordinator: Kirk, Gregory D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.