Leveraging HIV care to prevent liver cancer in Uganda
Official title: Leveraging HIV care infrastructure for implementation of context-adapted liver cancer comprehensive control strategies in Uganda: The LC3 Study
Funded at Johns Hopkins University · NIH-11535353 · Data updated 2026-11-12
A program in Uganda uses existing HIV care clinics to roll out a liver cancer prevention and treatment plan tailored to local needs.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 3, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $223,400 |
| NIH project number | 3U01CA275117-03S1 |
| Project ID | NIH-11535353 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with HIV in Uganda, particularly in regions with high HBV carriage and liver cancer risk.
✕Less likely to help
Patients without HIV or those not receiving HBV-related care may not directly benefit.
What this research studies
This project builds on long-running Uganda-US collaborations to bring HBV and HIV care together, aiming to prevent and detect liver cancer early within HIV clinics. It will adapt proven liver cancer strategies to Uganda’s context, including diagnostics, treatment pathways, and patient support. The team will implement and evaluate a bundled set of interventions designed to integrate HBV management, cancer screening, and care coordination into HIV services.
Why it matters
Potential benefit: If successful, people living with HIV in Uganda could receive earlier liver cancer prevention, diagnosis, and treatment within familiar care settings.
How similar studies have gone: Past implementation efforts showed feasibility and importance of context-adapted liver cancer care within HIV programs in Africa.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Kirk, Gregory D — Johns Hopkins University
- Study coordinator: Kirk, Gregory D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.