Investigating blood flow issues in glaucoma
Vascular dysfunction in glaucoma
This study is looking at how problems with blood flow might affect people with glaucoma, a condition that can lead to blindness, and it hopes to find out if improving blood flow could help those who are still losing their vision even with current treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-11191367 on NIH RePORTER |
What this research studies
This research focuses on understanding how blood flow abnormalities contribute to glaucoma, a leading cause of irreversible blindness. It aims to explore the relationship between elevated intraocular pressure and reduced blood flow, which may impair optic nerve function. Using advanced imaging techniques like multiparametric MRI, the study will assess blood flow and optic nerve health in both animal models and humans. The goal is to determine if improving blood flow could serve as a new treatment strategy for glaucoma patients who continue to lose vision despite current therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with glaucoma who are experiencing vision loss despite treatment.
Not a fit: Patients with glaucoma who have not been diagnosed or those whose vision loss is unrelated to blood flow issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options that improve vision preservation for glaucoma patients.
How similar studies have performed: Previous research has shown promising results in targeting blood flow abnormalities in glaucoma, suggesting that this approach may be viable.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Muir, Eric Raymond — Univ of North Carolina Chapel Hill
- Study coordinator: Muir, Eric Raymond
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.