NIH-funded research U01 cooperative agreement

Improving IBD outcomes and reducing disparities through everyday care, data, and education

Official title: RFA-DP-23-002, Improving Outcomes and Reducing Disparities for Patients with Inflammatory Bowel Disease through Epidemiology, Enhanced Disease Management, Dissemination, and Education

Funded at Univ of North Carolina Chapel Hill · NIH-11383272 · Data updated 2026-11-12

A multi-site program tests how social factors affect inflammatory bowel disease and whether new management and education can help people in diverse backgrounds feel better and stay healthier.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startSeptember 30, 2023
Project endSeptember 29, 2028
Funding year2026
Award (this year)$774,997
NIH project number5U01DP006745-04
Project IDNIH-11383272 on NIH RePORTER

Who could benefit from this research

Could help

Patients with Crohn’s disease or ulcerative colitis, including both children (13-17) and adults (>17) at participating sites.

Less likely to help

Patients not enrolled in the pragmatic trial or not experiencing social determinants affecting their care may see limited direct benefit.

What this research studies

This project follows people with Crohn’s disease and ulcerative colitis across multiple clinics to see how social circumstances influence disease progression and quality of life. It will test practical management strategies in real-world settings over a year and includes a large prospective group plus a built-in observational component. The effort also focuses on creating education for patients and clinicians that reflects what matters to diverse communities. The study is led by a team at UNC Chapel Hill and partners with pediatric and adult IBD centers to reach both children and adults.

Why it matters

Potential benefit: If successful, the program could reduce disparities in IBD care and improve daily living and outcomes for patients from diverse backgrounds.

How similar studies have gone: Prior studies suggest social factors influence IBD outcomes; this project builds on that by testing real-world management and education approaches.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Kappelman, Michael D — Univ of North Carolina Chapel Hill
  • Study coordinator: Kappelman, Michael D

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.