Improving how we diagnose acute heart failure
Improving Diagnostic Accuracy for Acute Heart Failure
This study is working on a new way to help doctors more accurately diagnose acute heart failure in patients who come to the emergency room with symptoms like shortness of breath, so they can get the right treatment faster and feel better sooner.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-10821378 on NIH RePORTER |
What this research studies
This research focuses on enhancing the accuracy of diagnosing acute heart failure (HF), a condition that can be easily confused with other illnesses due to overlapping symptoms. It aims to develop a multi-marker diagnostic model using advanced biomarker testing, particularly through plasma proteomics, to improve the identification of acute HF in emergency department settings. By addressing the limitations of previous studies, this research seeks to reduce misdiagnosis rates and improve patient outcomes. Patients presenting with symptoms like dyspnea will be evaluated using this innovative approach to diagnostic testing.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who present to the emergency department with symptoms of dyspnea and are suspected of having acute heart failure.
Not a fit: Patients with chronic heart failure or those who do not exhibit symptoms related to acute heart failure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses of acute heart failure, reducing misdiagnosis and improving treatment outcomes for patients.
How similar studies have performed: Previous research has shown promise in using multi-marker approaches for diagnosis, but this study aims to expand on those findings with a novel and comprehensive methodology.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Gupta, Deepak — Vanderbilt University Medical Center
- Study coordinator: Gupta, Deepak
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.