Understanding changes in kidney function during acute heart failure
Discriminating Causes of Creatinine Change in Acute Heart Failure
This study is looking into how heart failure affects kidney function, especially in veterans, to find specific markers that can help doctors understand the different reasons for kidney problems during heart failure, ultimately aiming to improve diagnosis and treatment for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA San Diego Healthcare System NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project ID | NIH-10975923 on NIH RePORTER |
What this research studies
This research investigates the causes of changes in kidney function that occur during acute heart failure, a condition that affects many patients, particularly veterans. The study aims to identify specific biomarkers that can help differentiate between various causes of kidney impairment in this context. By analyzing data and conducting clinical trials, the research seeks to improve the understanding of how heart failure impacts kidney health and vice versa. Patients may benefit from more accurate diagnoses and tailored treatments based on the findings.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients diagnosed with acute heart failure, particularly those who also have signs of kidney dysfunction.
Not a fit: Patients with stable heart conditions or those without any kidney issues may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for patients experiencing acute heart failure and related kidney issues.
How similar studies have performed: Previous research has shown promise in using biomarkers to understand heart-kidney interactions, indicating that this approach may yield valuable insights.
Where this research is happening
San Diego, United States
- VA San Diego Healthcare System — San Diego, United States (Active)
Researchers
- Principal investigator: Wettersten, Nicholas — VA San Diego Healthcare System
- Study coordinator: Wettersten, Nicholas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.