Understanding changes in kidney function during acute heart failure

Who could benefit from this research

What this research studies

This research investigates the causes of changes in kidney function that occur during acute heart failure, a condition that affects many patients, particularly veterans. The study aims to identify specific biomarkers that can help differentiate between various causes of kidney impairment in this context. By analyzing data and conducting clinical trials, the research seeks to improve the understanding of how heart failure impacts kidney health and vice versa. Patients may benefit from more accurate diagnoses and tailored treatments based on the findings.

Why it matters

Where this research is happening

• VA San Diego Healthcare System
  San Diego, United States Active

Researchers

• Principal investigator: Wettersten, Nicholas — VA San Diego Healthcare System
• Study coordinator: Wettersten, Nicholas

Related research

Other NIH-funded projects on the same topics.

• Using AI to monitor lung fluid in sudden (acute) heart failure in the ER

  This project will use an AI-assisted lung ultrasound method to track lung congestion in people who come to the emergency department with acute heart failure.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11267990

• Stepwise water‑pill (diuretic) plan versus usual care for people with acute heart failure in the emergency room

  This project compares a step-by-step plan for giving water pills to usual care to help people with sudden worsening heart failure in the emergency room remove extra fluid and feel better sooner.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11171538

• Using AI to monitor fluid buildup in patients with acute heart failure in emergency settings

  This study is looking at how using a special ultrasound tool can help doctors better check for fluid buildup in the lungs of patients with acute heart failure in emergency rooms, so they can get the right treatment faster and leave the hospital feeling better.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11048481

• Improving hospitalization decisions for emergency patients with heart failure

  This study is looking at how to help doctors decide if patients with acute heart failure should be admitted to the hospital or can safely recover at home, by considering important factors about their health and personal situations.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11013391

• Comparing two approaches to diuretic therapy for patients with acute heart failure in the emergency department

  This study is looking at whether a special plan for using diuretics can help people with acute heart failure feel better and recover faster in the emergency department compared to the usual care they receive.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-10907749

• Improving how we diagnose acute heart failure

  This study is working on a new way to help doctors more accurately diagnose acute heart failure in patients who come to the emergency room with symptoms like shortness of breath, so they can get the right treatment faster and feel better sooner.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-10821378

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.