Improving heart surgery outcomes by optimizing blood flow during surgery
Optimizing pulsatility during cardiopulmonary bypass to reduce acute kidney injury
This study is looking at how changing the way blood flows during heart surgery might help protect your kidneys and lower the chances of kidney problems afterward, so you can recover better after your operation.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10909850 on NIH RePORTER |
What this research studies
This research investigates how adjusting the pulsatility of blood flow during cardiopulmonary bypass can help protect kidney function and reduce the risk of acute kidney injury in patients undergoing cardiac surgery. The study aims to understand the relationship between blood flow patterns and organ health, particularly focusing on the kidneys, which can be adversely affected during surgery. By collaborating with a team of experts in various fields, the research seeks to develop innovative clinical practices that enhance patient recovery and outcomes after surgery.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals scheduled for cardiac surgery who are at risk of developing acute kidney injury.
Not a fit: Patients who are not undergoing cardiac surgery or those with pre-existing severe kidney disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of acute kidney injury in patients undergoing cardiac surgery, leading to better overall health outcomes.
How similar studies have performed: Previous research has shown promising results in optimizing blood flow during surgeries, indicating that this approach could lead to significant advancements in patient care.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Clendenen, Nathan — University of Colorado Denver
- Study coordinator: Clendenen, Nathan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.