SEAK Alliance: Improving Care for AKI Patients in the Southeast
Official title: The Southeastern Acute Kidney Injury (SEAK) Alliance for the COPE-AKI Consortium
Funded at Vanderbilt University Medical Center · NIH-11518282 · Data updated 2026-11-12
A national, patient-centered effort to improve post-hospital care for people who had acute kidney injury in the Southeast.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | July 19, 2021 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $952,935 |
| NIH project number | 5U01DK129989-06 |
| Project ID | NIH-11518282 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults who have experienced AKI and are receiving care at participating Southeastern academic medical centers.
✕Less likely to help
Patients not receiving post-AKI care or who are not followed at participating sites may not directly benefit.
What this research studies
This grant focuses on understanding and improving how AKI survivors are cared for after leaving the hospital, with attention to barriers faced by patients in the Southeastern US. The project will engage care teams at academic medical centers to track recovery, coordinate follow-up, and optimize kidney-protective treatments and medications. By addressing gaps in monitoring and support, it aims to reduce the risk of CKD, cardiovascular problems, rehospitalization, and poor quality of life for AKI survivors. The work will leverage existing clinics and data to identify practical interventions that can be implemented in real-world settings.
Why it matters
Potential benefit: If successful, patients who survive AKI could experience better kidney recovery, fewer complications, and a smoother transition from hospital to home.
How similar studies have gone: Previous efforts have shown that structured post-AKI care can improve outcomes, but regional disparities remain and further implementation is needed.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Siew, Edward D — Vanderbilt University Medical Center
- Study coordinator: Siew, Edward D
Related research
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A machine-learning approach uses routinely collected hospital data to predict who might develop acute kidney injury after heart surgery, so clinicians can act early.
-
Norepinephrine vs phenylephrine to reduce kidney injury after major non-cardiac surgery
A large, real-world trial will compare two common vasopressors to see which helps prevent kidney injury after major non-heart surgeries.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.