NIH-funded research R01 grant

Improving glaucoma detection and prediction using artificial intelligence.

Official title: SCH: Robust and Equitable Clinical Decision Support in Glaucoma Detection and Progression Prediction

Funded at University of Pennsylvania · NIH-11063429 · Data updated 2026-11-12

This study is working on a smart tool that uses artificial intelligence to help doctors spot and predict glaucoma earlier by looking at different types of eye tests, so patients can get better care and keep their vision longer.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania
NIH-funded
Lab location1 site (Philadelphia, United States)
Project startSeptember 1, 2024
Project endAugust 31, 2028
Funding year2024
Award (this year)$300,001
NIH project number1R01EY037101-01
Project IDNIH-11063429 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals at risk for glaucoma or those experiencing early symptoms of vision impairment.

Less likely to help

Patients with advanced glaucoma who have already experienced significant vision loss may not benefit from this research.

What this research studies

This research focuses on enhancing the detection and prediction of glaucoma, a progressive eye disease that can lead to vision loss. By developing an artificial intelligence-based clinical decision support tool, the project aims to integrate various types of patient data, such as retinal imaging and visual field measurements, to improve diagnostic accuracy. The tool will also be designed to help clinicians make informed decisions by providing clear insights into the AI's predictions and uncertainties. Ultimately, this approach seeks to facilitate earlier interventions and better management of glaucoma.

Why it matters

Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of glaucoma, potentially preventing vision loss for many patients.

How similar studies have gone: Previous research has shown promise in using AI for disease detection, suggesting that this approach could lead to significant advancements in glaucoma management.

Where this research is happening

  • University of Pennsylvania
    Philadelphia, United States
    Active

Researchers

  • Principal investigator: Lee, Insup — University of Pennsylvania
  • Study coordinator: Lee, Insup

Related research

Other NIH-funded projects on the same topics.

  • IOP and CSF Pressure in Glaucoma Risk

    This grant studies how eye pressure and cerebrospinal fluid pressure together influence glaucoma risk and vision loss.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11644421

  • Comparing tube positions in glaucoma implants to protect corneal cells

    This trial compares two tube placements for glaucoma drainage implants to see which better protects corneal cells and controls eye pressure in people with uncontrolled glaucoma.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-11520347

  • Automated topographic test for glaucoma detection and progression

    A new automated method uses topographic structure-function mapping to help diagnose glaucoma earlier and track its progression in patients.

    NIH research Columbia University Health Sciences · New York, United States · NIH-11516608

  • Using AI on eye scans and genes to predict glaucoma risk

    This project uses artificial intelligence on eye scans, vision tests, and genetic information to find people most likely to develop or have worsening glaucoma.

    NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11469603

  • AI-based glaucoma screening in community health centers

    A new, easy-to-use AI screening approach will be tested in federally funded health centers to help identify people at risk for glaucoma, especially in communities with higher risk.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11454104

  • Understanding how glaucoma genes control eye cell function

    A long-term research project will study how genetic factors affect eye cells in adults with glaucoma to uncover new ideas for protecting vision.

    NIH research Massachusetts Eye and Ear Infirmary · Boston, United States · NIH-11450761

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.