Improving deep brain stimulation for Parkinson's disease
Pathophysiology-based approaches to deep brain stimulation for Parkinson's disease
This study is looking at how to make deep brain stimulation work better for people with Parkinson's disease by understanding the brain circuits involved, so that treatments can be tailored to each person's unique needs and help manage their symptoms more effectively.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10930875 on NIH RePORTER |
What this research studies
This research investigates how deep brain stimulation (DBS) can be optimized for patients with Parkinson's disease by understanding the brain circuits involved in the disease. The study focuses on the basal ganglia thalamocortical circuit and aims to identify how these circuits change with DBS and medication. By analyzing brain activity and connectivity, researchers hope to develop personalized DBS treatments that target specific brain regions based on individual motor and cognitive profiles. This approach could lead to more effective therapies for managing symptoms of Parkinson's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's disease who are considering or currently undergoing deep brain stimulation therapy.
Not a fit: Patients with Parkinson's disease who are not candidates for deep brain stimulation or those with advanced stages of the disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments for Parkinson's disease, improving patients' quality of life.
How similar studies have performed: Previous research has shown promise in optimizing deep brain stimulation techniques, indicating that this approach could build on existing knowledge.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Vitek, Jerrold L — University of Minnesota
- Study coordinator: Vitek, Jerrold L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.