Identifying risk factors for ALS through patient data analysis
Official title: RFA-TS-23-001: Assessment of ALS Risk Factors from ALS TDI's Ongoing Natural History Study (n = 784)
Funded at Als Therapy Development Foundation · NIH-10913283 · Data updated 2026-11-12
This study is looking at what might increase the risk of developing or worsening ALS by gathering information from people living with the condition, so we can better understand how health, lifestyle, and environment play a role.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Als Therapy Development Foundation NIH-funded |
| Lab location | 1 site (Watertown, United States) |
| Project start | September 30, 2023 |
| Project end | September 29, 2025 |
| Funding year | 2024 |
| Award (this year) | $480,595 |
| NIH project number | 5R01TS000341-02 |
| Project ID | NIH-10913283 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with amyotrophic lateral sclerosis who are willing to participate in ongoing data collection and analysis.
✕Less likely to help
Patients who do not have a diagnosis of ALS or are unable to provide the necessary data for analysis may not benefit from this research.
What this research studies
This research investigates the risk factors associated with amyotrophic lateral sclerosis (ALS) by analyzing data collected from individuals living with the condition. The study involves a longitudinal approach, where participants provide extensive information about their health, lifestyle, and environmental factors through surveys administered every three months. Additionally, clinical data such as functional ratings, voice recordings, activity levels, and blood samples are collected to gain insights into the progression of ALS and its potential risk factors. The goal is to identify and confirm factors that may contribute to the development or progression of ALS.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of ALS risk factors, potentially guiding prevention strategies and personalized treatment options for patients.
How similar studies have gone: Previous research has shown success in identifying risk factors for ALS through similar longitudinal cohort studies, indicating that this approach is both valid and promising.
Where this research is happening
-
Als Therapy Development Foundation
Watertown, United States Active
Researchers
- Principal investigator: Vieira, Fernando Gameiro — Als Therapy Development Foundation
- Study coordinator: Vieira, Fernando Gameiro
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.