How blood cell activity changes during aortic valve replacement
Patient-specific blood cell reactivity and flow dynamic profiles in transcatheter aortic valve replacement
This study is looking at how differences in your blood cells can impact your recovery after getting a new heart valve through a procedure called TAVR, with the hope of finding ways to make your experience better and reduce complications.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-11002674 on NIH RePORTER |
What this research studies
This research investigates how individual differences in blood cell behavior affect outcomes in patients undergoing transcatheter aortic valve replacement (TAVR). By analyzing patient-specific factors such as blood flow dynamics and biochemical responses, the study aims to understand how these variations contribute to complications like inflammation and clotting. The research employs advanced experimental techniques to explore the relationship between these factors and the performance of artificial heart valves. Ultimately, the goal is to improve patient management and outcomes in those with aortic valve diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with aortic valve diseases who are scheduled for transcatheter aortic valve replacement.
Not a fit: Patients who are not undergoing TAVR or have other unrelated cardiovascular conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management strategies for patients undergoing aortic valve replacement, reducing complications and improving recovery.
How similar studies have performed: Previous research has shown promising results in understanding blood cell dynamics in cardiovascular procedures, suggesting that this approach could yield valuable insights.
Where this research is happening
Portland, United States
- Oregon Health & Science University — Portland, United States (Active)
Researchers
- Principal investigator: Hinds, Monica T — Oregon Health & Science University
- Study coordinator: Hinds, Monica T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.