NIH-funded research R01 grant

Fruit-flavored e-cigarettes and smoking reduction in adults who smoke

Official title: Assessing whether use of fruit flavored ENDS relates to smoking reductions in people who smoke cigarettes: A data triangulation approach to maximize internal and external validity

Funded at Roswell Park Cancer Institute Corp · NIH-11341677 · Data updated 2026-11-12

This grant studies whether using fruit-flavored e-cigarettes helps adults who smoke reduce or quit smoking.

More Smoking research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRoswell Park Cancer Institute Corp
NIH-funded
Lab location1 site (Buffalo, United States)
Project startAugust 1, 2026
Project endJuly 31, 2031
Funding year2026
Award (this year)$867,448
NIH project number1R01DA065590-01
Project IDNIH-11341677 on NIH RePORTER

Who could benefit from this research

Could help

Adults 21+ who currently smoke cigarettes and may use ENDS as a harm-reduction strategy.

Less likely to help

Individuals who do not use ENDS or who do not intend to reduce cigarette smoking may derive little direct benefit.

What this research studies

Researchers will analyze how fruit-flavored ENDS use relates to changes in smoking behavior among adults who smoke cigarettes. The project uses data from multiple sources to understand the full path from trying ENDS to long-term smoking abstinence. The aim is to inform policies on flavored products with real-world data, not experimentation in a lab setting. Results could help guide decisions that affect adults who smoke and their options for reducing harm.

Why it matters

Potential benefit: If successful, findings could help refine regulations to maximize harm reduction for people who smoke.

How similar studies have gone: Previous research on flavors and smoking behavior is limited and findings have been inconsistent, making this study notably novel.

Where this research is happening

  • Roswell Park Cancer Institute Corp
    Buffalo, United States
    Active

Researchers

  • Principal investigator: Goniewicz, Maciej Lukasz — Roswell Park Cancer Institute Corp
  • Study coordinator: Goniewicz, Maciej Lukasz

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.