Diabetes that develops after acute pancreatitis
Official title: Epidemiology and Pathophysiology of Acute Pancreatitis-related Diabetes Mellitus
Funded at Ohio State University · NIH-11234780 · Data updated 2026-11-12
This project follows people who've had acute pancreatitis to find out why and how often they develop diabetes.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | September 17, 2020 |
| Project end | July 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $492,500 |
| NIH project number | 2U01DK127388-06 |
| Project ID | NIH-11234780 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults who recently had an episode of acute pancreatitis and can attend periodic follow-up visits and blood tests are ideal candidates.
✕Less likely to help
People whose diabetes began before their pancreatitis or who cannot complete follow-up visits and testing are unlikely to benefit directly.
What this research studies
If you join, you'll be followed after an episode of acute pancreatitis with regular blood tests and health checks to see if and when diabetes appears. The study is part of a multi-center consortium with leadership from Ohio State and collects blood samples, medical records, diet information, scans, and other data over several years. Researchers will look for signs of autoimmunity, pancreatic damage, and dietary or metabolic factors that might explain why diabetes develops in some people but not others. The goal is to use these repeated tests and data to help doctors spot high-risk patients earlier and design better prevention or treatment strategies.
Why it matters
Potential benefit: Could identify who is at highest risk for diabetes after pancreatitis so they can receive earlier monitoring, prevention, or tailored treatment.
How similar studies have gone: Previous smaller or retrospective studies suggest post-pancreatitis diabetes is common but were limited, so this prospective multi-center effort is a newer, more comprehensive approach.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Papachristou, Georgios I — Ohio State University
- Study coordinator: Papachristou, Georgios I
Related research
Other NIH-funded projects on the same topics.
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Epidemiology and causes of diabetes after acute pancreatitis
A long-term study following people who have had acute pancreatitis to understand how often diabetes develops, why it happens, and how it progresses.
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Understanding diabetes that develops after acute pancreatitis
This study is looking at how having a sudden inflammation of the pancreas, called acute pancreatitis, might lead to diabetes later on, and it’s for people who have experienced this condition to help find better ways to prevent and treat diabetes.
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Diabetes after acute pancreatitis: understanding and tracking progression
A patient-focused look at how diabetes can develop after an episode of acute pancreatitis, using data from a large, ongoing study and AI insights.
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Continuation of Type 1 Diabetes in Acute Pancreatitis: UF Health and AdventHealth
A patient-facing overview of a long-term study tracking people with acute pancreatitis to understand how some develop type 1 diabetes later and what factors influence that process.
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Data Coordinating Center for Type 1 Diabetes in Acute Pancreatitis Consortium
A national effort to learn how pancreatitis-related Type 1 diabetes develops, by tracking patients and coordinating data to improve future care.
-
Diabetes after acute pancreatitis: a patient-focused network study
A program at Indiana University is studying how diabetes can develop after an acute pancreatitis episode, with new findings that could help doctors tailor care for adults who had pancreatitis.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.