Endometriosis and heart disease risk in women with reproductive history details
Official title: Endometriosis Diagnosis and Subtypes, Reproductive History, and Cardiovascular Disease
Funded at Utah State Higher Education System--University of Utah · NIH-11383429 · Data updated 2026-11-12
This grant studies whether women with endometriosis have higher chances of developing heart and blood vessel problems, using large health records to follow outcomes over many years.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Utah State Higher Education System--University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project start | May 9, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $658,517 |
| NIH project number | 5R01HL164715-04 |
| Project ID | NIH-11383429 on NIH RePORTER |
Who could benefit from this research
✓Could help
Women with endometriosis and a history of reproductive events who are followed in large cohort datasets and have long-term health records.
✕Less likely to help
Women without endometriosis or without available long-term cardiovascular data may not benefit from these findings.
What this research studies
For patients, the project will use real-world medical data from large groups of women to see if endometriosis, its subtypes, and reproductive histories are linked to later heart and vascular diseases. The study will combine two existing cohorts—the Utah Population Database and the NICHD ENDO study—to examine both clinical events and subclinical signs of cardiovascular disease. By understanding how different endometriosis profiles relate to cardiovascular risk, clinicians may better identify high-risk patients and tailor preventive care. The research will emphasize long-term follow-up and comprehensive data analysis to capture timing and severity of outcomes across diverse populations.
Why it matters
Potential benefit: If successful, the work could improve how doctors monitor heart health in women with endometriosis and guide personalized prevention strategies.
How similar studies have gone: Previous studies suggest a link between endometriosis and cardiovascular risk, but significant gaps remain that this project aims to fill with long follow-up and subtype analysis.
Where this research is happening
-
Utah State Higher Education System--University of Utah
Salt Lake City, United States Active
Researchers
- Principal investigator: Schliep, Karen C. — Utah State Higher Education System--University of Utah
- Study coordinator: Schliep, Karen C.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.