Investigating heart disease risk in women with endometriosis
Official title: Mechanisms and interventions addressing accelerated cardiovascular disease risk in women with endometriosis
Funded at Pennsylvania State University, the · NIH-11239443 · Data updated 2026-11-12
This study is looking at how endometriosis might raise the risk of heart problems in women and how common treatments for endometriosis could affect heart health, with the goal of finding better ways to keep both your reproductive and heart health in check.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State University, the NIH-funded |
| Lab location | 1 site (University Park, United States) |
| Project start | January 5, 2022 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $87,918 |
| NIH project number | 3R01HL161000-04S1 |
| Project ID | NIH-11239443 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women diagnosed with endometriosis who are concerned about their cardiovascular health.
✕Less likely to help
Patients without endometriosis or those who do not have cardiovascular disease risk factors may not benefit from this research.
What this research studies
This research focuses on understanding how endometriosis, a condition affecting many women, may increase the risk of cardiovascular disease (CVD). It explores the inflammatory processes involved and how standard treatments for endometriosis, which suppress estrogen, can complicate heart health. By examining the role of specific biological markers and signaling pathways, the research aims to identify effective interventions to reduce cardiovascular risks in these patients. The study seeks to bridge the gap between managing endometriosis and protecting heart health.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing cardiovascular disease risk in women with endometriosis.
How similar studies have gone: Previous research has indicated a link between endometriosis and increased cardiovascular risk, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Pennsylvania State University, the
University Park, United States Active
Researchers
- Principal investigator: Alexander, Lacy M. — Pennsylvania State University, the
- Study coordinator: Alexander, Lacy M.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.