Investigating heart disease risk in women with endometriosis

Mechanisms and interventions addressing accelerated cardiovascular disease risk in women with endometriosis

NIH-funded research Pennsylvania State University, the · NIH-11239443

This study is looking at how endometriosis might raise the risk of heart problems in women and how common treatments for endometriosis could affect heart health, with the goal of finding better ways to keep both your reproductive and heart health in check.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionPennsylvania State University, the NIH-funded
Lab location1 site (University Park, United States)
Project IDNIH-11239443 on NIH RePORTER

What this research studies

This research focuses on understanding how endometriosis, a condition affecting many women, may increase the risk of cardiovascular disease (CVD). It explores the inflammatory processes involved and how standard treatments for endometriosis, which suppress estrogen, can complicate heart health. By examining the role of specific biological markers and signaling pathways, the research aims to identify effective interventions to reduce cardiovascular risks in these patients. The study seeks to bridge the gap between managing endometriosis and protecting heart health.

Who could benefit from this research

Good fit: Ideal candidates for this research are women diagnosed with endometriosis who are concerned about their cardiovascular health.

Not a fit: Patients without endometriosis or those who do not have cardiovascular disease risk factors may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for managing cardiovascular disease risk in women with endometriosis.

How similar studies have performed: Previous research has indicated a link between endometriosis and increased cardiovascular risk, suggesting that this approach could yield valuable insights.

Where this research is happening

University Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Atherosclerotic Cardiovascular Diseaseatherosclerotic diseaseatherosclerotic vascular disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.