Understanding heart disease risk in women with endometriosis
Official title: Mechanisms and interventions addressing accelerated cardiovascular disease risk in women with endometriosis
Funded at Pennsylvania State University, the · NIH-11009004 · Data updated 2026-11-12
This study is looking at how endometriosis might raise the risk of heart problems in women and aims to find ways to help manage this risk better, so if you have endometriosis, your participation could help improve care for you and others like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State University, the NIH-funded |
| Lab location | 1 site (University Park, United States) |
| Project start | January 5, 2022 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $673,576 |
| NIH project number | 5R01HL161000-04 |
| Project ID | NIH-11009004 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women diagnosed with endometriosis who are at risk for cardiovascular disease.
✕Less likely to help
Patients without endometriosis or those who do not have cardiovascular disease risk factors may not benefit from this research.
What this research studies
This research investigates how endometriosis, a condition affecting many women, may increase the risk of cardiovascular disease due to inflammation and hormonal treatments. It aims to explore the mechanisms behind this connection and identify effective interventions to reduce cardiovascular risks. By examining the role of inflammatory markers and specific receptors in the body, the study seeks to provide insights that could lead to better management strategies for women suffering from both endometriosis and heart disease. Patients may be involved in assessments that help clarify these relationships and test new treatment approaches.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing cardiovascular health in women with endometriosis.
How similar studies have gone: Previous research has indicated a link between inflammation and cardiovascular disease, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Pennsylvania State University, the
University Park, United States Active
Researchers
- Principal investigator: Alexander, Lacy M. — Pennsylvania State University, the
- Study coordinator: Alexander, Lacy M.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.