Economic and relationship program to help couples reduce heavy drinking in Malawi

A randomized controlled trial of an economic and relationship-strengthening intervention to reduce alcohol use in Malawi

NIH-funded research University of California, San Francisco · NIH-11380573

This program helps couples affected by HIV in Malawi cut heavy drinking by combining money-management support with relationship and communication skills.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-11380573 on NIH RePORTER

What this research studies

You and your partner would learn practical ways to redirect money spent on alcohol into savings or small investments while also building communication and relationship skills. The Mlambe program brings couples together for sessions that mix economic coaching, peer support, and relationship-strengthening activities. Couples are randomly assigned to receive Mlambe or the usual services so researchers can compare drinking, couple conflict, and HIV treatment adherence over time. A small pilot showed the program was acceptable to couples and had promising early effects.

Who could benefit from this research

Good fit: Ideal candidates are couples in Malawi affected by HIV—especially where a male partner reports heavy alcohol use—who are willing to attend joint sessions on finances and relationships.

Not a fit: People without problematic alcohol use, single individuals, or those living outside Malawi would be unlikely to benefit directly from this program.

Why it matters

Potential benefit: If successful, it could lower heavy drinking, protect family finances, improve couple relationships, and help people stay on HIV treatment.

How similar studies have performed: A prior pilot trial of Mlambe showed feasibility and promising impacts, though combining economic and couples approaches in sub-Saharan Africa is relatively novel.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.